Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | LPL | P06858 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257658 | 1.00 | ENPP2 (0.55) | ENPP2FFAR1NPC1RAB9AMAOA | |
| SCHEMBL257853 | 0.92 | ENPP2 (0.50) | ENPP2FFAR1MAOAMAOBSIRT2 | |
| SCHEMBL12030691 | 0.90 | ENPP2 (0.58) | ENPP2FFAR1NPC1RAB9AMGLL | |
| SCHEMBL25233864 | 0.86 | ENPP2 (0.51) | ENPP2FFAR1MAOAMAOBSIRT2 | |
| SCHEMBL31050995 | 0.86 | ENPP2 (0.51) | ENPP2FFAR1MAOAMAOBSIRT2 | |
| SCHEMBL29953375 | 0.86 | LTA4H (0.49) | ENPP2FFAR1LPLLIPG | |
| SCHEMBL22315 | 0.83 | CYP4F2 (0.58) | ENPP2RAB9AMAOAMAOBCYP4F2 | |
| SCHEMBL17912866 | 0.82 | NPC1 (0.60) | FFAR1NPC1RAB9AMAOAMAOB | |
| SCHEMBL2574765 | 0.82 | ENPP2 (0.45) | ENPP2MAOBCYP4F2CYP4A11 | |
| SCHEMBL12663136 | 0.81 | FFAR1 (0.54) | ENPP2FFAR1NPC1RAB9ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761413-B | Carbapenem hydrolysis D-type beta-lactamase inhibitor and preparation method thereof | 明知大学校产学协力团 | 2024-04-12 | — | — | CN | claimed |
| CN-114761413-A | Carbapenem hydrolysis D-type beta-lactamase inhibitor and preparation method thereof | 明知大学校产学协力团 | 2022-07-15 | — | — | CN | claimed |
| CN-114761413-B | Carbapenem hydrolysis D-type beta-lactamase inhibitor and preparation method thereof | 明知大学校产学协力团 | 2024-04-12 | — | — | CN | disclosed |
| CN-114761413-B | Carbapenem hydrolysis D-type beta-lactamase inhibitor and preparation method thereof | 明知大学校产学协力团 | 2024-04-12 | — | — | CN | disclosed |
| CN-114761413-A | Carbapenem hydrolysis D-type beta-lactamase inhibitor and preparation method thereof | 明知大学校产学协力团 | 2022-07-15 | — | — | CN | disclosed |
| CN-114761413-A | Carbapenem hydrolysis D-type beta-lactamase inhibitor and preparation method thereof | 明知大学校产学协力团 | 2022-07-15 | — | — | CN | disclosed |