Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.64 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 16/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22944363 | 1.00 | PARP1 (0.64) | PARP1HCRTR1HCRTR2FKBP1AKDM4E | |
| SCHEMBL22944360 | 0.78 | DRD1 (0.48) | PARP1FKBP1A | |
| SCHEMBL29795294 | 0.78 | DRD1 (0.48) | PARP1FKBP1A | |
| SCHEMBL29672353 | 0.74 | PARP1 (0.43) | PARP1FKBP1AKDM4EKMT2A | |
| SCHEMBL4535899 | 0.66 | HCRTR2 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL9173929 | 0.65 | DPP4 (0.58) | PARP1KDM4EKMT2A | |
| SCHEMBL22944117 | 0.64 | HDAC6 (0.41) | KDM4EKMT2A | |
| SCHEMBL29672374 | 0.64 | HDAC6 (0.41) | KDM4EKMT2A | |
| SCHEMBL29672403 | 0.64 | HDAC6 (0.41) | KDM4EKMT2A | |
| SCHEMBL12878934 | 0.64 | PARP1 (0.51) | PARP1FKBP1AKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528767-B2 | HDAC6 inhibitors and uses thereof | EIKONIZO THERAPEUTICS, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-20220281814-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2022-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220281814-A1 | HDAC6 INHIBITORS AND USES THEREOF | HDAC6, HDAC1, HDAC5 | PARP1 769/4885HCRTR1 3361/4885HCRTR2 3514/4885 |
| US-12528767-B2 | HDAC6 inhibitors and uses thereof | HDAC6, HDAC1, HDAC11 | PARP1 789/4885HCRTR1 912/4885HCRTR2 1153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.