Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 4/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29784646 | 0.78 | KDM4E (0.38) | KDM4EKMT2A | |
| SCHEMBL22944360 | 0.77 | DRD1 (0.48) | PARP1DRD1HTR1ADRD2FKBP1A | |
| SCHEMBL29795294 | 0.77 | DRD1 (0.48) | PARP1DRD1HTR1ADRD2FKBP1A | |
| SCHEMBL29795228 | 0.74 | PARP1 (0.64) | PARP1KDM4EKMT2AFKBP1A | |
| SCHEMBL22944363 | 0.74 | PARP1 (0.64) | PARP1KDM4EKMT2AFKBP1A | |
| SCHEMBL38655143 | 0.61 | HCRTR1 (0.41) | HTR1A | |
| SCHEMBL21341950 | 0.61 | HTR2A (0.48) | DRD2 | |
| SCHEMBL29672373 | 0.60 | MEN1 (0.33) | KMT2A | |
| SCHEMBL1248603 | 0.60 | SLC6A4 (0.51) | DRD1DRD2 | |
| SCHEMBL24120795 | 0.59 | HCRTR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528767-B2 | HDAC6 inhibitors and uses thereof | EIKONIZO THERAPEUTICS, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-20220281814-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2022-09-08 | — | — | US | disclosed |
| EP-4003319-A2 | HDAC6 INHIBITORS AND USES THEREOF | Eikonizo Therapeutics, Inc. (US) | 2022-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220281814-A1 | HDAC6 INHIBITORS AND USES THEREOF | HDAC6, HDAC1, HDAC5 | PARP1 769/4885DRD1 4606/4885HTR1A 3577/4885 |
| US-12528767-B2 | HDAC6 inhibitors and uses thereof | HDAC6, HDAC1, HDAC11 | PARP1 789/4885DRD1 3882/4885HTR1A 2072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.