Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 5/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29795294 | 1.00 | DRD1 (0.48) | DRD1PARP1HTR1ACHRNA7DRD2 | |
| SCHEMBL22944364 | 0.79 | DRD2 (0.39) | DRD1CHRNA7DRD2DRD4DRD5 | |
| SCHEMBL22944367 | 0.79 | HDAC6 (0.41) | — | |
| SCHEMBL22944368 | 0.79 | HDAC6 (0.41) | — | |
| SCHEMBL22944361 | 0.79 | HDAC6 (0.41) | — | |
| SCHEMBL29795228 | 0.78 | PARP1 (0.64) | PARP1FKBP1A | |
| SCHEMBL22944363 | 0.78 | PARP1 (0.64) | PARP1FKBP1A | |
| SCHEMBL29672353 | 0.77 | PARP1 (0.43) | DRD1PARP1HTR1ADRD2FKBP1A | |
| SCHEMBL29795180 | 0.75 | DRD1 (0.64) | DRD1CHRNA7DRD2DRD4DRD5 | |
| SCHEMBL22944117 | 0.74 | HDAC6 (0.41) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021979-A2 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPAPEUTICS, INC. (US) | 2021-02-04 | — | — | WO | disclosed |