Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16616673 | 0.95 | KDM4E (0.72) | KDM4EHSD17B10L3MBTL1GAAALDH1A1 | |
| SCHEMBL23120406 | 0.87 | GAA (0.48) | KDM4EHSD17B10L3MBTL1GAAALDH1A1 | |
| SCHEMBL10254012 | 0.85 | KDM4E (0.62) | KDM4EHSD17B10L3MBTL1GAAALDH1A1 | |
| SCHEMBL17294334 | 0.83 | KDM4E (0.64) | KDM4EHSD17B10L3MBTL1GAAALDH1A1 | |
| SCHEMBL29795714 | 0.82 | KDM4E (0.50) | KDM4EHSD17B10L3MBTL1GAAALDH1A1 | |
| SCHEMBL29795644 | 0.82 | KDM4E (0.60) | KDM4EHSD17B10L3MBTL1GAAALDH1A1 | |
| SCHEMBL2229192 | 0.80 | GAA (0.71) | KDM4EHSD17B10L3MBTL1GAAALDH1A1 | |
| SCHEMBL11470029 | 0.80 | KDM4E (0.69) | KDM4EHSD17B10L3MBTL1GAAALDH1A1 | |
| SCHEMBL3227432 | 0.80 | KDM4E (0.71) | KDM4EHSD17B10L3MBTL1GAAALDH1A1 | |
| SCHEMBL16624286 | 0.79 | KDM4E (0.55) | KDM4EHSD17B10L3MBTL1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4031545-A1 | PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2022-07-27 | — | — | EP | disclosed |