SCHEMBL23120406

SCHEMBL23120406

Cc1nc(O)c(C#N)cc1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.48
SMN1; SMN2 Q16637 4/20 0.47
ALDH1A1 P00352 6/20 0.46
KDM4E B2RXH2 5/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
LMNA P02545 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HPGD P15428 1/20 0.42
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29795690 0.87 KDM4E (0.66) GAASMN1; SMN2ALDH1A1KDM4EHSD17B10
SCHEMBL11489099 0.86 KDM4E (0.53) GAASMN1; SMN2ALDH1A1KDM4EHSD17B10
SCHEMBL10461860 0.86 ALDH1A1 (0.60) GAASMN1; SMN2ALDH1A1KDM4EHSD17B10
SCHEMBL5027025 0.84 KDM4E (0.41) GAASMN1; SMN2ALDH1A1KDM4EHSD17B10
SCHEMBL2229192 0.82 GAA (0.71) GAASMN1; SMN2ALDH1A1KDM4EHSD17B10
SCHEMBL4098277 0.81 CYP1A2 (0.53) GAASMN1; SMN2ALDH1A1KDM4EHSD17B10
SCHEMBL16616673 0.80 KDM4E (0.72) GAASMN1; SMN2ALDH1A1KDM4EHSD17B10
SCHEMBL14190689 0.79 SMN1; SMN2 (0.47) GAASMN1; SMN2ALDH1A1KDM4EHSD17B10
SCHEMBL31030218 0.79 L3MBTL1 (0.68) GAASMN1; SMN2ALDH1A1KDM4EHSD17B10
SCHEMBL31030177 0.78 GAA (0.43) GAASMN1; SMN2ALDH1A1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114401963-B Pesticidally active cyclic amine compounds 先正达农作物保护股份公司 2025-03-14 CN disclosed
US-20220389000-A1 PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-12-08 US disclosed
US-20220389000-A1 PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-12-08 US disclosed
EP-4031545-A1 PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS Syngenta Crop Protection AG (CH) 2022-07-27 EP disclosed
CN-114401963-A Pesticidally active cyclic amine compounds 先正达农作物保护股份公司 2022-04-26 CN disclosed
WO-2021053161-A1 PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2021-03-25 WO disclosed
WO-2021053161-A1 PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2021-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220389000-A1 PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS DDT, ACHE, PNMT GAA 3455/4885SMN1; SMN2 852/4885ALDH1A1 1079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.