Propiconazole

Propiconazole

SCHEMBL29795708

CCC[C@@H]1CO[C@](Cn2cncn2)(c2ccc(Cl)cc2Cl)O1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 16/20 1.00
THRB P10828 1/20 0.86
HSP90AA1 P07900 2/20 0.64
NPSR1 Q6W5P4 1/20 0.64
LMNA P02545 2/20 0.60
FYN P06241 2/20 0.60
CYP51A1 Q16850 2/20 0.60
ADRA1A P35348 2/20 0.60
NR1I2 O75469 1/20 0.60
PGR P06401 1/20 0.60
CHRM2 P08172 1/20 0.60
CHRM4 P08173 1/20 0.60
CHRM5 P08912 1/20 0.60
ADRA2A P08913 1/20 0.60
CHRM1 P11229 1/20 0.60
TSHR P16473 1/20 0.60
ADRA2B P18089 1/20 0.60
ADRA2C P18825 1/20 0.60
CHRM3 P20309 1/20 0.60
DRD1 P21728 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propiconazole SCHEMBL5598958 1.00 CYP3A4 (1.00) CYP3A4THRBHSP90AA1NPSR1LMNA
Propiconazole SCHEMBL3005219 1.00 CYP3A4 (1.00) CYP3A4THRBHSP90AA1NPSR1LMNA
Propiconazole SCHEMBL21081 1.00 CYP3A4 (1.00) CYP3A4THRBHSP90AA1NPSR1LMNA
Propiconazole SCHEMBL29404305 1.00 CYP3A4 (1.00) CYP3A4THRBHSP90AA1NPSR1LMNA
Propiconazole SCHEMBL9321555 1.00 CYP3A4 (1.00) CYP3A4THRBHSP90AA1NPSR1LMNA
Propiconazole SCHEMBL30149161 1.00 CYP3A4 (1.00) CYP3A4THRBHSP90AA1NPSR1LMNA
Propiconazole SCHEMBL30182039 1.00 CYP3A4 (1.00) CYP3A4THRBHSP90AA1NPSR1LMNA
Propiconazole SCHEMBL2522027 1.00 CYP3A4 (1.00) CYP3A4THRBHSP90AA1NPSR1LMNA
Propiconazole SCHEMBL23804502 0.99 CYP3A4 (0.98) CYP3A4THRBHSP90AA1NPSR1LMNA
Propiconazole SCHEMBL28518788 0.99 CYP3A4 (0.98) CYP3A4THRBHSP90AA1NPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4331364-A2 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO Corteva Agriscience LLC (US) 2024-03-06 EP claimed
CN-121914078-A Post-treatment method for propiconazole synthesis 江苏优嘉植物保护有限公司 2026-04-24 CN disclosed
US-20250338846-A1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE, LLC (US) 2025-11-06 US disclosed
CN-119907626-A Compositions having pesticidal utility and methods related thereto 科迪华农业科技有限责任公司 2025-04-29 CN disclosed
EP-4525618-A2 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO Corteva Agriscience LLC (US) 2025-03-26 EP disclosed
US-20240334932-A1 POLYMORPHS HAVING PESTICIDAL ACTIVITY CORTEVA AGRISCIENCE LLC 2024-10-10 US disclosed
US-20240188560-A1 STABLE EMULSIONS ADAMA AGAN LTD. (IL) 2024-06-13 US disclosed
CN-118043320-A Polymorphs having pesticidal activity 科迪华农业科技有限责任公司 2024-05-14 CN disclosed
EP-4331364-A2 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO Corteva Agriscience LLC (US) 2024-03-06 EP disclosed
EP-4051003-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2023-11-29 EP disclosed
WO-2023224815-A2 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2023-11-23 WO disclosed
US-20230189807-A1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2023-06-22 US disclosed
WO-2022208501-A1 STABLE EMULSIONS ADAMA AGAN LTD. (IL) 2022-10-06 WO disclosed
EP-4066638-A1 STABLE EMULSIONS Adama Agan Ltd. (IL) 2022-10-05 EP disclosed
EP-4066639-A1 STABLE EMULSIONS Adama Agan Ltd. (IL) 2022-10-05 EP disclosed
CN-115052482-A Compositions having pesticidal utility and methods relating thereto 科迪华农业科技有限责任公司 2022-09-13 CN disclosed
EP-4051003-A1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO Corteva Agriscience LLC (US) 2022-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250338846-A1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO ACHE, DDT, PLA2G2D CYP3A4 1401/4885THRB 3837/4885HSP90AA1 1015/4885
US-20240188560-A1 STABLE EMULSIONS POLR2H, POLR2E, PHOSPHO1 CYP3A4 3603/4885THRB 2009/4885HSP90AA1 2127/4885
US-20240334932-A1 POLYMORPHS HAVING PESTICIDAL ACTIVITY PTMS, DDT, PTMA CYP3A4 27/4885THRB 1094/4885HSP90AA1 2365/4885
US-20230189807-A1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO ACHE, DDT, PLA2G2D CYP3A4 2278/4885THRB 3257/4885HSP90AA1 975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.