Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29796117 | 0.91 | HTR1A (0.47) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL29796226 | 0.89 | DRD2 (0.49) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL29796155 | 0.88 | HTR1A (0.49) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL29796035 | 0.86 | HTR1A (0.52) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL29796243 | 0.83 | DRD2 (0.62) | HTR1ADRD2HTR2A | |
| SCHEMBL29796084 | 0.81 | DRD2 (0.62) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL23409256 | 0.77 | DRD2 (0.55) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL30728642 | 0.77 | DRD2 (0.55) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL23409248 | 0.75 | DRD2 (0.53) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL23409258 | 0.74 | DRD2 (0.55) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728956-A | Fused heterocyclic derivative and application thereof | 上海枢境生物科技有限公司 | 2022-07-08 | — | — | CN | disclosed |