Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 14/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1510186 | 0.88 | FFAR1 (0.69) | KEAP1FFAR1FFAR4CA1CA2 | |
| SCHEMBL241358 | 0.87 | HDAC3 (0.67) | KEAP1FFAR1HDAC3MAPK1ADRA1A | |
| Phenyl Propionic Acid SCHEMBL7707231 | 0.85 | KEAP1 (0.76) | KEAP1FFAR1FFAR4HDAC3MAPK1 | |
| SCHEMBL298309 | 0.85 | MAPT (0.66) | KEAP1FFAR1HDAC3MAPK1ADRA1A | |
| SCHEMBL7496474 | 0.84 | MAPT (0.69) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL6937997 | 0.83 | FFAR1 (0.72) | FFAR1FFAR4 | |
| SCHEMBL69746 | 0.83 | FFAR1 (0.81) | KEAP1FFAR1FFAR4CA1CA2 | |
| Phenyl Propionic Acid SCHEMBL8901632 | 0.81 | KEAP1 (0.95) | KEAP1FFAR1FFAR4HDAC3MAPK1 | |
| Phenyl Propionic Acid SCHEMBL9122761 | 0.81 | KEAP1 (0.95) | KEAP1FFAR1FFAR4HDAC3MAPK1 | |
| Phenyl Propionic Acid SCHEMBL5314808 | 0.81 | KEAP1 (0.95) | KEAP1FFAR1FFAR4HDAC3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113845427-B | Aryl alcohol, aryl ketone, aryl carboxylic acid compound, and synthetic method and application thereof | 华东师范大学 | 2024-06-25 | — | — | CN | claimed |
| CN-111196819-B | D-A-D type benzopyrazines compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-03-28 | — | — | CN | claimed |
| CN-111196819-A | D-A-D type benzopyrazines compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2020-05-26 | — | — | CN | claimed |
| CN-110396284-A | A kind of expansion type flame retardant, flame-retardant polylactic acid material and preparation method thereof | UNIV NANJING SCI & TECH | 2019-11-01 | — | — | CN | claimed |
| CN-109810491-A | A kind of flame retardant type high voltage power cable | 安徽天康(集团)股份有限公司 | 2019-05-28 | — | — | CN | claimed |
| CN-108892936-A | A kind of High glow wire halogen-free flame retardant PBT-EPDM-PP alloy material and preparation method thereof | 安徽长淮新材料有限公司 | 2018-11-27 | — | — | CN | claimed |
| CN-108517120-A | A kind of ageing-resistant silastic material and preparation method thereof | 天长市荣盛有机硅科技有限公司 | 2018-09-11 | — | — | CN | claimed |
| CN-108441100-A | A kind of high-ductility flame retardant polyurethane coating | 天长市巨龙车船涂料有限公司 | 2018-08-24 | — | — | CN | claimed |
| CN-108441102-A | A kind of wear-resisting fire prevention water paint | 天长市巨龙车船涂料有限公司 | 2018-08-24 | — | — | CN | claimed |
| CN-108440966-A | A kind of environment protection heat-proof flame-proof silicon rubber and preparation method thereof | 天长市荣盛有机硅科技有限公司 | 2018-08-24 | — | — | CN | claimed |
| WO-2003041649-A2 | CYANOALKYLAMINO DERIVATIVES AS PROTEASE INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2003-05-22 | — | — | WO | claimed |
| US-5837719-A | USEFUL FOR TREATING CYTOKINE MEDIATED DISEASES, INFLAMMATION,SHOCK, ARTHRITIS, RESPIRATORY DISORDERS, THROMBOSIS, VIRAL INFECTION, GASTROINTESTINAL DISORDERS | MERCK & CO., INC. (US) | 1998-11-17 | — | — | US | claimed |
| EP-0869967-A2 | INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME | Vertex Pharmaceuticals Incorporated (US) | 1998-10-14 | — | — | EP | claimed |
| US-5756466-A | Inhibitors of interleukin-1β converting enzyme | VERTEX PHARMACEUTICALS, INC. (US) | 1998-05-26 | — | — | US | claimed |
| WO-1997022619-A2 | INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1997-06-26 | — | — | WO | claimed |
| EP-0567967-B1 | Tritium-labelled fibrinogen-receptor-antagonists, their use and their production | THOMAE GMBH DR K (DE) | 1996-07-10 | — | — | EP | claimed |
| US-5527476-A | RHODIUM CATALYST FOR CROSSLINKING METHYLHYDROGENSILOXANES IN TREATING FIBERS OR FABRICS | DOW CORNING CORPORATION (US) | 1996-06-18 | — | — | US | claimed |
| WO-1995024405-A1 | IMIDAZOLIDIN-2-ONES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND METHOD OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1995-09-14 | — | — | WO | claimed |
| US-5409620-A | Fiber treatment compositions containing organofunctional siloxanes and methods for the preparation thereof | DOW CORNING CORPORATION (US) | 1995-04-25 | — | — | US | claimed |
| US-4182897-A | ENZYME INHIBITORS FOR PROTEOLYTIC ENZYMES | TORII & CO., LTD. (JP) | 1980-01-08 | — | — | US | claimed |