SCHEMBL6937997

SCHEMBL6937997

O=C(O)CCc1ccc(C#Cc2cc[c]cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.72
FFAR4 Q5NUL3 5/20 0.72
CHRM2 P08172 1/20 0.57
S1PR1 P21453 1/20 0.57
FPR1 P21462 1/20 0.57
FPR3 P25089 1/20 0.57
GPR183 P32249 1/20 0.57
APLNR P35414 1/20 0.57
GPR65 Q8IYL9 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1551253 0.84 FFAR1 (1.00) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL297973 0.83 KEAP1 (0.64) FFAR1FFAR4
SCHEMBL18165302 0.82 FFAR1 (0.77) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL240565 0.82 FFAR1 (0.70) FFAR1FFAR4
SCHEMBL12087474 0.81 FFAR1 (1.00) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL1510186 0.80 FFAR1 (0.69) FFAR1FFAR4
SCHEMBL1550238 0.79 FFAR1 (1.00) FFAR1FFAR4
SCHEMBL1337387 0.78 FFAR1 (0.69) FFAR1FFAR4
SCHEMBL22540433 0.78 FFAR1 (0.70) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL1550173 0.77 FFAR1 (1.00) FFAR1FFAR4CHRM2S1PR1FPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6603070-B2 Convergent method for the synthesis of light harvesting rods. The rods are oligomers of the formula A1(Ab+1)b, wherein b is at least 1, A1 through Ab+1 are covalently coupled rod segments, and each rod segment A1 through A1+b comprises a NORTH CAROLINA STATE UNIVERSITY 2003-08-05 US disclosed
US-6596935-B2 Chromophores absorb light and exhibit intrinsic molecular level rectification in the flow of excited-state energy and ground-state holes NORTH CAROLINA STATE UNIVERSITY 2003-07-22 US disclosed
US-20030111108-A1 Convergent synthesis of multiporphyrin light-harvesting rods UNITED STATES DEPARTMENT OF ENERGY 2003-06-19 US disclosed
EP-1319255-A1 LIGHT HARVESTING ARRAYS NORTH CAROLINA STATE UNIVERSITY (US) 2003-06-18 EP disclosed
EP-1303884-A1 SOLAR CELLS INCORPORATING LIGHT HARVESTING ARRAYS NORTH CAROLINA STATE UNIVERSITY (US) 2003-04-23 EP disclosed
WO-2003019621-A2 CONVERGENT SYNTHESIS OF MULTIPORPHYRIN LIGHT-HARVESTING RODS NORTH CAROLINA STATE UNIVERSITY (US) 2003-03-06 WO disclosed
US-20020185173-A1 Solar cells incorporating light harvesting arrays NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2002-12-12 US disclosed
US-6420648-B1 SOLAR CELLS NORTH CAROLINA STATE UNIVERSITY 2002-07-16 US disclosed
US-6407330-B1 A CIRCUIT ELECTRICALLY COUPLED TO SAID SOLAR CELL; LIGHT HARVESTING RODS OF NON-DISCOTIC BACKBONE POLYMER CONTAINING CHROMOPHORE GROUPS NORTH CAROLINA STATE UNIVERSITY 2002-06-18 US disclosed
WO-2002009196-A1 LIGHT HARVESTING ARRAYS NORTH CAROLINA STATE UNIVERSITY (US) 2002-01-31 WO disclosed
WO-2002009197-A1 SOLAR CELLS INCORPORATING LIGHT HARVESTING ARRAYS NORTH CAROLINA STATE UNIVERSITY (US) 2002-01-31 WO disclosed