Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29798219 | 0.88 | HPGD (0.35) | MAPK1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL29798045 | 0.84 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL21952020 | 0.83 | MAPK1 (0.53) | MAPK1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL24209741 | 0.78 | HPGD (0.57) | MAPK1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL30296113 | 0.78 | KMT2A (0.56) | MAPK1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL24019614 | 0.76 | TSHR (0.53) | MAPK1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL14557267 | 0.72 | ALDH1A1 (0.48) | MAPK1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21952062 | 0.70 | HPGD (0.47) | MAPK1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL21952090 | 0.69 | RECQL (0.53) | MAPK1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29798043 | 0.67 | MAPT (0.50) | MAPK1MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4149461-A1 | UBIQUITIN-LIGASE INHIBITORS FOR THE TREATMENT OF CANCER | Fundación Profesor Novoa Santos (ES) | 2023-03-22 | — | — | EP | disclosed |
| WO-2021229035-A9 | UBIQUITIN-LIGASE INHIBITORS FOR THE TREATMENT OF CANCER | FUNDACIÓN PROFESOR NOVOA SANTOS (ES) | 2022-09-09 | — | — | WO | disclosed |