Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21952003 | 0.85 | MEN1 (0.45) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL29797997 | 0.84 | MAPK1 (0.44) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL29798219 | 0.82 | HPGD (0.35) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL29798210 | 0.80 | MAPT (0.47) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL24209741 | 0.73 | HPGD (0.57) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL14557267 | 0.69 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL21952020 | 0.67 | MAPK1 (0.53) | ALDH1A1KMT2AMEN1HPGDGAA | |
| SCHEMBL21952062 | 0.66 | HPGD (0.47) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL29798098 | 0.65 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL21952090 | 0.64 | RECQL (0.53) | ALDH1A1KMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4149461-A1 | UBIQUITIN-LIGASE INHIBITORS FOR THE TREATMENT OF CANCER | Fundación Profesor Novoa Santos (ES) | 2023-03-22 | — | — | EP | disclosed |
| WO-2021229035-A9 | UBIQUITIN-LIGASE INHIBITORS FOR THE TREATMENT OF CANCER | FUNDACIÓN PROFESOR NOVOA SANTOS (ES) | 2022-09-09 | — | — | WO | disclosed |