Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 17/20 | 0.60 |
| ▸ | CTSD | P07339 | 2/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | NPY4R | P50391 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29798176 | 0.95 | BACE1 (0.65) | BACE1CTSDBACE2 | |
| SCHEMBL29798029 | 0.95 | BACE1 (0.59) | BACE1CTSDOPRK1BACE2NPY1R | |
| SCHEMBL29798338 | 0.92 | BACE1 (0.63) | BACE1CTSDBACE2 | |
| SCHEMBL29798061 | 0.92 | NPY4R (0.58) | BACE1CTSDOPRK1NPY1RNPY2R | |
| SCHEMBL29798264 | 0.90 | BACE1 (0.64) | BACE1CTSDOPRK1BACE2 | |
| SCHEMBL29415210 | 0.89 | BACE1 (0.61) | BACE1CTSDOPRK1BACE2NPY1R | |
| SCHEMBL30616041 | 0.88 | OPRK1 (0.58) | BACE1CTSDOPRK1BACE2NPY1R | |
| SCHEMBL17935594 | 0.88 | BACE1 (0.57) | BACE1CTSDOPRK1BACE2NPY1R | |
| SCHEMBL29659768 | 0.88 | OPRK1 (0.58) | BACE1CTSDOPRK1BACE2NPY1R | |
| SCHEMBL31393817 | 0.88 | BACE1 (0.62) | BACE1CTSDOPRK1BACE2NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220259265-A1 | Inhibitors and Use Thereof in Cancer Treatment | THE UNIVERSITY OF SYDNEY (AU) | 2022-08-18 | — | — | US | disclosed |