SCHEMBL29659768

SCHEMBL29659768

CC(C)C[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O)C(C)C

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 2/20 0.58
BACE1 P56817 13/20 0.58
BACE2 Q9Y5Z0 3/20 0.58
CTSD P07339 1/20 0.58
NPY1R P25929 1/20 0.56
NPY2R P49146 1/20 0.56
NPY4R P50391 1/20 0.56
NTSR2 O95665 1/20 0.53
NTSR1 P30989 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30616041 1.00 OPRK1 (0.58) OPRK1BACE1BACE2CTSDNPY1R
SCHEMBL29415210 0.97 BACE1 (0.61) OPRK1BACE1BACE2CTSDNPY1R
SCHEMBL5576870 0.96 OPRK1 (0.63) OPRK1BACE1BACE2CTSD
SCHEMBL5576866 0.96 OPRK1 (0.63) OPRK1BACE1BACE2CTSD
SCHEMBL31393817 0.96 BACE1 (0.62) OPRK1BACE1BACE2CTSDNPY1R
SCHEMBL10379927 0.95 GNPAT (0.54) OPRK1BACE1BACE2CTSDNPY1R
SCHEMBL10379929 0.95 GNPAT (0.54) OPRK1BACE1BACE2CTSDNPY1R
SCHEMBL30616045 0.94 OPRK1 (0.60) OPRK1BACE1BACE2CTSD
SCHEMBL30570972 0.94 OPRK1 (0.60) OPRK1BACE1BACE2CTSD
SCHEMBL29496478 0.94 MMP2 (0.54) OPRK1BACE1BACE2CTSDNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114920798-A Self-assembly material constructed in situ at wound part and preparation method and application thereof 国家纳米科学中心 2022-08-19 CN claimed
CN-114920798-A Self-assembly material constructed in situ at wound part and preparation method and application thereof 国家纳米科学中心 2022-08-19 CN disclosed
CN-109942714-B Functional polypeptide and application 中国药科大学 2022-07-08 CN disclosed