Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21952023 | 0.85 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL31396267 | 0.85 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL31396264 | 0.83 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL21952059 | 0.83 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL29798225 | 0.82 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL29798314 | 0.81 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AMAPK1TSHR | |
| SCHEMBL29798321 | 0.78 | CPB1 (0.47) | ALDH1A1L3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL21952094 | 0.76 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL31396379 | 0.76 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL29798204 | 0.75 | TSHR (0.61) | ALDH1A1MEN1KMT2AMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4149461-A1 | UBIQUITIN-LIGASE INHIBITORS FOR THE TREATMENT OF CANCER | Fundación Profesor Novoa Santos (ES) | 2023-03-22 | — | — | EP | disclosed |
| WO-2021229035-A9 | UBIQUITIN-LIGASE INHIBITORS FOR THE TREATMENT OF CANCER | FUNDACIÓN PROFESOR NOVOA SANTOS (ES) | 2022-09-09 | — | — | WO | disclosed |