Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30664668 | 0.85 | HSP90AA1 (0.39) | TAAR1RAB9ANPC1ALDH1A1ATM | |
| SCHEMBL24683224 | 0.85 | HSP90AA1 (0.39) | TAAR1RAB9ANPC1ALDH1A1ATM | |
| SCHEMBL29799825 | 0.81 | KMT2A (0.41) | MAOBALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL29799950 | 0.78 | MAPT (0.38) | RAB9AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL24682970 | 0.78 | KMT2A (0.36) | MAOBRAB9ANPC1ALDH1A1ATM | |
| SCHEMBL29799916 | 0.77 | KMT2A (0.34) | MAOBRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL29799716 | 0.77 | MEN1 (0.46) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL24682820 | 0.75 | KMT2A (0.35) | RAB9AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL24683191 | 0.75 | HSP90AA1 (0.38) | RAB9ANPC1ALDH1A1ATML3MBTL1 | |
| SCHEMBL30664665 | 0.75 | HSP90AA1 (0.38) | RAB9ANPC1ALDH1A1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |