Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30664665 | 0.91 | HSP90AA1 (0.38) | KMT2AMEN1CLCN2ALDH1A1KDM4E | |
| SCHEMBL24683191 | 0.91 | HSP90AA1 (0.38) | KMT2AMEN1CLCN2ALDH1A1KDM4E | |
| SCHEMBL30701705 | 0.90 | MCL1 (0.39) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL24683876 | 0.90 | MCL1 (0.39) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL24682820 | 0.89 | KMT2A (0.35) | KMT2AMEN1CLCN2ALDH1A1KDM4E | |
| SCHEMBL29799909 | 0.88 | BCKDK (0.35) | KMT2AMEN1MAOBRIPK1 | |
| SCHEMBL24683895 | 0.88 | BCKDK (0.35) | KMT2AMEN1MAOBRIPK1 | |
| SCHEMBL29800055 | 0.86 | TSPO (0.40) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL24682198 | 0.86 | TSPO (0.40) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL24683224 | 0.82 | HSP90AA1 (0.39) | ALDH1A1KDM4EATMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222630-A | 2-acetamido-6-hydroxy-benzothiophene derivatives having antiviral activity | OTC制药公司(JSC) | 2023-12-12 | — | — | CN | disclosed |
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |