SCHEMBL29800293

SCHEMBL29800293

Cc1ccc([C@H](CO)CCCO)cc1C

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
TRPA1 O75762 1/20 0.32
PTGS1 P23219 1/20 0.32
CACNA1C Q13936 1/20 0.32
BRD4 O60885 1/20 0.32
CCL2 P13500 1/20 0.32
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
SLC6A3 Q01959 1/20 0.32
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28830535 1.00 ALDH1A1 (0.41) ALDH1A1TRPA1PTGS1CACNA1CBRD4
SCHEMBL28830537 1.00 ALDH1A1 (0.41) ALDH1A1TRPA1PTGS1CACNA1CBRD4
SCHEMBL28830455 0.79 CHRNA7 (0.39) ALDH1A1
SCHEMBL28830454 0.79 CHRNA7 (0.39) ALDH1A1
SCHEMBL29800155 0.77 ACP3 (0.39)
SCHEMBL28830485 0.77 ACP3 (0.39)
SCHEMBL28830483 0.77 ACP3 (0.39)
SCHEMBL27347833 0.76 HPGD (0.35) ALDH1A1TP53
SCHEMBL28830526 0.76 HPGD (0.35) ALDH1A1TP53
SCHEMBL6002859 0.72 TRPA1 (0.39) ALDH1A1TRPA1PTGS1CACNA1CTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957304-A Chiral 1, 5-diborane compound and synthesis method and application thereof 浙江大学 2022-08-30 CN disclosed