Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29800812 | 1.00 | ALDH1A1 (0.42) | ALDH1A1SLC40A1KMT2ATDP1MEN1 | |
| SCHEMBL26964361 | 1.00 | ALDH1A1 (0.42) | ALDH1A1SLC40A1KMT2ATDP1MEN1 | |
| SCHEMBL30553402 | 0.86 | SLC40A1 (0.43) | ALDH1A1SLC40A1TDP1LMNAHTT | |
| SCHEMBL26964376 | 0.86 | SLC40A1 (0.43) | ALDH1A1SLC40A1TDP1LMNAHTT | |
| SCHEMBL29800922 | 0.85 | EDNRA (0.37) | ALDH1A1SLC40A1KMT2ATDP1MEN1 | |
| SCHEMBL27214232 | 0.85 | EDNRA (0.37) | ALDH1A1SLC40A1KMT2ATDP1MEN1 | |
| SCHEMBL26964470 | 0.78 | ALDH1A1 (0.44) | ALDH1A1SLC40A1KMT2ATDP1MEN1 | |
| SCHEMBL29800857 | 0.78 | ALDH1A1 (0.44) | ALDH1A1SLC40A1KMT2ATDP1MEN1 | |
| SCHEMBL6985112 | 0.78 | ALDH1A1 (0.64) | ALDH1A1SLC40A1KMT2ATDP1MEN1 | |
| SCHEMBL30925585 | 0.77 | ALDH1A1 (0.40) | ALDH1A1SLC40A1KMT2ATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4291555-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2023-12-20 | — | — | EP | disclosed |
| WO-2022173727-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-08-18 | — | — | WO | disclosed |