Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 6/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24975179 | 1.00 | SCN2A (0.45) | SCN2ASCN10ASMN1; SMN2PIK3CAROCK2 | |
| SCHEMBL29801147 | 0.86 | SMN1; SMN2 (0.42) | SCN2ASCN10ASMN1; SMN2ROCK2KDM4E | |
| SCHEMBL24975336 | 0.86 | SMN1; SMN2 (0.42) | SCN2ASCN10ASMN1; SMN2ROCK2KDM4E | |
| SCHEMBL29996168 | 0.85 | PIK3CA (0.46) | SCN2ASCN10ASMN1; SMN2PIK3CAROCK2 | |
| SCHEMBL29995413 | 0.82 | LMNA (0.54) | LMNAPOLBHTT | |
| SCHEMBL29854301 | 0.76 | MCHR1 (0.46) | SCN2ASCN10APIK3CALMNAPOLB | |
| SCHEMBL24975301 | 0.76 | MCHR1 (0.46) | SCN2ASCN10APIK3CALMNAPOLB | |
| SCHEMBL24975171 | 0.76 | SCN2A (0.44) | SCN2ASCN10APIK3CAROCK2KDM4E | |
| SCHEMBL29801166 | 0.76 | SCN2A (0.44) | SCN2ASCN10APIK3CAROCK2KDM4E | |
| SCHEMBL29995782 | 0.75 | LMNA (0.44) | SCN2ASCN10ASMN1; SMN2ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930509-A | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-114929672-B | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2025-01-21 | — | — | CN | disclosed |
| EP-4055008-A1 | CANCER TREATMENTS TARGETING CANCER STEM CELLS | Remedy Plan, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |
| CN-114929672-A | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2022-08-19 | — | — | CN | disclosed |