SCHEMBL29996168

SCHEMBL29996168

CCC(=O)N(C)c1ccc(-c2ccc(C(=O)NCc3cccnc3C)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PIK3CA P42336 1/20 0.46
▸ KMT2A Q03164 2/20 0.45
▸ MEN1 O00255 1/20 0.45
▸ LMNA P02545 3/20 0.44
▸ NPC1 O15118 1/20 0.44
▸ POLB P06746 1/20 0.44
▸ RAB9A P51151 1/20 0.44
▸ SCN2A Q99250 2/20 0.43
▸ SCN10A Q9Y5Y9 2/20 0.43
▸ HTT P42858 1/20 0.42
▸ ROCK2 O75116 2/20 0.42
▸ ROCK1 Q13464 2/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ CYP2C9 P11712 2/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ CYP2D6 P10635 1/20 0.41
▸ TAOK1 Q7L7X3 1/20 0.40
▸ TAOK3 Q9H2K8 1/20 0.40
▸ HPGD P15428 2/20 0.40
▸ AGTR1 P30556 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29854301 0.90 MCHR1 (0.46) PIK3CAKMT2AMEN1LMNAPOLB
SCHEMBL24975301 0.90 MCHR1 (0.46) PIK3CAKMT2AMEN1LMNAPOLB
SCHEMBL29995782 0.89 LMNA (0.44) KMT2AMEN1LMNANPC1POLB
SCHEMBL24975179 0.85 SCN2A (0.45) PIK3CALMNANPC1POLBRAB9A
SCHEMBL29801075 0.85 SCN2A (0.45) PIK3CALMNANPC1POLBRAB9A
SCHEMBL29854310 0.80 SCN2A (0.50) LMNAPOLBSCN2ASCN10ASMN1; SMN2
SCHEMBL24975175 0.80 SCN2A (0.50) LMNAPOLBSCN2ASCN10ASMN1; SMN2
SCHEMBL23063790 0.79 LMNA (0.64) KMT2ALMNAPOLBHTTSMN1; SMN2
SCHEMBL31253080 0.79 LMNA (0.64) KMT2ALMNAPOLBHTTSMN1; SMN2
SCHEMBL17888306 0.78 PIK3CA (0.55) PIK3CAKMT2AMEN1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125367-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS REMEDY PLAN, INC. (US) 2026-05-07 — — US disclosed
US-12522587-B2 Cancer treatments targeting cancer stem cells REMEDY PLAN, INC. (US) 2026-01-13 — — US disclosed
CN-119775198-A Cancer therapy targeting cancer stem cells 治疗方案股份有限公司 2025-04-08 — — CN disclosed
CN-112312899-B Cancer therapy targeting cancer stem cells 治疗方案股份有限公司 2024-11-22 — — CN disclosed
US-20220324842-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS REMEDY PLAN, INC. (US) 2022-10-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125367-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS MCL1, MALT1, BCL6 PIK3CA 2502/4885KMT2A 1185/4885MEN1 1108/4885
US-20220324842-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS MCL1, CD47, GLI1 PIK3CA 141/4885KMT2A 450/4885MEN1 279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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