Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | ESRRG | P62508 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | IL2 | P60568 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BCL6 | P41182 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669946 | 0.94 | TP53 (0.42) | WDR5TP53SMN1; SMN2HTR6ESRRG | |
| Trifluoroacetic Acid SCHEMBL29803840 | 0.87 | MAPT (0.39) | WDR5TP53SMN1; SMN2HTR6ESRRG | |
| Trifluoroacetic Acid SCHEMBL29803606 | 0.87 | TP53 (0.47) | WDR5TP53SMN1; SMN2ESRRGESR1 | |
| Trifluoroacetic Acid SCHEMBL29803663 | 0.80 | KDM4E (0.40) | TP53SMN1; SMN2HTR6ESRRGESR1 | |
| Trifluoroacetic Acid SCHEMBL29803386 | 0.80 | MAPKAPK2 (0.46) | TP53SMN1; SMN2ESRRGESR1ESR2 | |
| SCHEMBL24671113 | 0.80 | TP53 (0.49) | TP53SMN1; SMN2ESRRGESR1ESR2 | |
| SCHEMBL24671298 | 0.80 | ESRRG (0.43) | TP53HTR6ESRRGESR1ESR2 | |
| SCHEMBL29803912 | 0.80 | TP53 (0.49) | TP53SMN1; SMN2ESRRGESR1ESR2 | |
| Trifluoroacetic Acid SCHEMBL29803398 | 0.78 | IMPDH2 (0.41) | SMN1; SMN2BRPF1CDK9CCNT1BCL6 | |
| Trifluoroacetic Acid SCHEMBL29803624 | 0.76 | ESRRG (0.35) | TP53SMN1; SMN2ESRRGESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |