SCHEMBL29803786

SCHEMBL29803786

Cc1cc(C2=CCNCC2)ccc1C(=O)Nc1ccc(C2=CCNCC2)c(F)c1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CCNT1 O60563 3/20 0.42
CDK9 P50750 3/20 0.42
MAPKAPK2 P49137 1/20 0.42
NAMPT P43490 1/20 0.41
QDPR P09417 3/20 0.40
ERN1 O75460 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
WDR5 P61964 1/20 0.38
BRPF1 P55201 1/20 0.38
HTR6 P50406 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
HTR2C P28335 2/20 0.37
SLC2A1 P11166 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24671286 1.00 CCNT1 (0.42) CCNT1CDK9MAPKAPK2NAMPTQDPR
Trifluoroacetic Acid SCHEMBL29803744 0.94 ERN1 (0.40) CCNT1CDK9MAPKAPK2NAMPTQDPR
SCHEMBL29803699 0.91 MAPKAPK2 (0.44) CCNT1CDK9MAPKAPK2NAMPTQDPR
SCHEMBL24669469 0.91 CCNT1 (0.48) CCNT1CDK9MAPKAPK2NAMPTQDPR
SCHEMBL29803592 0.88 CCNT1 (0.41) CCNT1CDK9MAPKAPK2NAMPTQDPR
SCHEMBL29803746 0.88 CCNT1 (0.42) CCNT1CDK9MAPKAPK2NAMPTQDPR
Trifluoroacetic Acid SCHEMBL29803493 0.86 MAPKAPK2 (0.40) CCNT1CDK9MAPKAPK2NAMPTQDPR
SCHEMBL29803519 0.86 WDR5 (0.46) CCNT1CDK9MAPKAPK2NAMPTQDPR
SCHEMBL29803369 0.86 QDPR (0.49) CCNT1CDK9MAPKAPK2NAMPTQDPR
Hydrochloric Acid SCHEMBL29803628 0.86 MAPKAPK2 (0.40) CCNT1CDK9MAPKAPK2NAMPTQDPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022192162-A1 NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) 2022-09-15 WO disclosed