Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30678436 | 1.00 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2C19ALDH1A1HPGD | |
| SCHEMBL24683460 | 1.00 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2C19ALDH1A1HPGD | |
| SCHEMBL24682685 | 0.95 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2C19ALDH1A1HPGD | |
| SCHEMBL24683818 | 0.89 | TRPA1 (0.42) | CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30678399 | 0.88 | HPGD (0.39) | HPGDSMN1; SMN2SCN10A | |
| SCHEMBL29804295 | 0.88 | HPGD (0.39) | HPGDSMN1; SMN2SCN10A | |
| SCHEMBL24683531 | 0.88 | HPGD (0.39) | HPGDSMN1; SMN2SCN10A | |
| SCHEMBL24682687 | 0.88 | HPGD (0.41) | CYP1A2CYP2C19ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29804297 | 0.88 | HPGD (0.39) | HPGDSMN1; SMN2SCN10A | |
| SCHEMBL24682622 | 0.86 | ALDH1A1 (0.42) | ALDH1A1HPGDSMN1; SMN2SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4304585-A2 | METHYL-SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | Latigo Biotherapeutics, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| CN-117062607-A | Methyl substituted pyridine and pyridazine compounds, derivatives thereof and methods of use thereof | 拉堤果生物医疗股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| WO-2022192487-A2 | METHYL-SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2022-09-15 | — | — | WO | disclosed |