Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23754190 | 1.00 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1KDM4EHTTKMT2A | |
| SCHEMBL2912781 | 0.80 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1KDM4EHTTKMT2A | |
| SCHEMBL846431 | 0.80 | KMT2A (0.36) | ALDH1A1KMT2AMEN1NPSR1TDP1 | |
| SCHEMBL8655458 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EHTTTSHRHSD17B10 | |
| SCHEMBL3830239 | 0.77 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1KDM4EHTTKMT2A | |
| SCHEMBL23754325 | 0.77 | TTR (0.36) | — | |
| SCHEMBL18956948 | 0.77 | KDM4E (0.36) | ALDH1A1L3MBTL1KDM4EHTTKMT2A | |
| SCHEMBL23776483 | 0.77 | ALDH1A1 (0.32) | ALDH1A1NPSR1TDP1 | |
| SCHEMBL22208226 | 0.77 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1KDM4EHTTKMT2A | |
| SCHEMBL30064854 | 0.77 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1KDM4EHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4304585-A2 | METHYL-SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | Latigo Biotherapeutics, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022192487-A2 | METHYL-SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2022-09-15 | — | — | WO | disclosed |