Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND3 | P30281 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15894822 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4EABL1HSD17B10HTT | |
| SCHEMBL10690802 | 0.78 | KDM4E (0.44) | ALDH1A1KDM4EABL1HSD17B10HTT | |
| SCHEMBL8648853 | 0.77 | HTT (0.47) | ALDH1A1KDM4EABL1HSD17B10HTT | |
| SCHEMBL30937680 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EABL1HSD17B10HTT | |
| SCHEMBL23754325 | 0.77 | TTR (0.36) | CDK4CCND3 | |
| SCHEMBL23754190 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10HTTTSHR | |
| SCHEMBL29804248 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10HTTTSHR | |
| SCHEMBL11551515 | 0.74 | NOS3 (0.42) | ALDH1A1KDM4EABL1HSD17B10HTT | |
| SCHEMBL8865549 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4EABL1HSD17B10HTT | |
| SCHEMBL24373080 | 0.73 | KDM4E (0.43) | ALDH1A1KDM4EABL1HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710157-A | INSECTICIDES FOR AGRICULTURE | FMC CORPORATION (US) | 1998-01-20 | — | — | US | disclosed |
| US-5593998-A | 2,4-diamino-5,6-disubstituted-and 5,6,7-trisubstituted-5-deazapteridines as insecticides | FMC CORPORATION (US) | 1997-01-14 | — | — | US | disclosed |
| US-5547954-A | MIXED WITH AGRICULTURAL ACCEPTABLE CARRIER | FMC CORPORATION (US) | 1996-08-20 | — | — | US | disclosed |
| US-5532370-A | FOR INSECTS INCLUDING LARVAE SUCH AS TOBACCO BUDWORM | FMC CORPORATION (US) | 1996-07-02 | — | — | US | disclosed |