Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.77 |
| ▸ | SPR | P35270 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.67 |
| ▸ | HTR2C | P28335 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | HTR1A | P08908 | 2/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | HTR2A | P28223 | 2/20 | 0.67 |
| ▸ | HTR2B | P41595 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.67 |
| ▸ | HTR7 | P34969 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20168582 | 1.00 | HDAC8 (0.77) | HDAC8SPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL20168578 | 1.00 | HDAC8 (0.77) | HDAC8SPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL5121693 | 0.91 | NPSR1 (0.67) | HDAC8SPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL24277478 | 0.91 | SPR (0.74) | HDAC8SPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL6399249 | 0.91 | SPR (0.74) | HDAC8SPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL15145410 | 0.90 | HDAC8 (0.68) | HDAC8SPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL15145420 | 0.87 | SPR (0.77) | HDAC8SPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL10407441 | 0.87 | NPSR1 (0.69) | HDAC8SPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL10407439 | 0.87 | NPSR1 (0.69) | HDAC8SPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL5108712 | 0.86 | NPSR1 (0.62) | HDAC8SPRKDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177581-B | Myeloperoxidase imaging agents | 通用医疗公司 | 2023-01-03 | — | — | CN | disclosed |
| EP-4076542-A1 | HIGHLY EFFICIENT MYELOPEROXIDASE ACTIVATABLE IMAGING AGENTS | The General Hospital Corporation (US) | 2022-10-26 | — | — | EP | disclosed |
| CN-114828900-A | High efficiency myeloperoxidase activatable imaging agents | 总医院公司 | 2022-07-29 | — | — | CN | disclosed |