Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550745 | 0.88 | — | — | |
| SCHEMBL11250686 | 0.82 | POLB (0.32) | POLB | |
| SCHEMBL19049542 | 0.80 | SMN1; SMN2 (0.33) | POLB | |
| SCHEMBL11255550 | 0.80 | POLB (0.31) | POLB | |
| SCHEMBL5181718 | 0.78 | POLB (0.30) | POLBAR | |
| SCHEMBL2981814 | 0.78 | LMNA (0.33) | — | |
| SCHEMBL376221 | 0.77 | MMP1 (0.33) | POLB | |
| SCHEMBL133836 | 0.77 | POLB (0.39) | POLBAR | |
| SCHEMBL8638714 | 0.75 | DAO (0.38) | — | |
| SCHEMBL11642326 | 0.75 | POLB (0.38) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943377-B | Cellulose antibacterial material with lysine grafted N-halamine type Schiff base structure and preparation method thereof | 长春工业大学 | 2023-03-21 | — | — | CN | claimed |
| CN-113943377-A | Cellulose antibacterial material with lysine grafted N-halamine type Schiff base structure and preparation method thereof | 长春工业大学 | 2022-01-18 | — | — | CN | claimed |
| CN-113943377-B | Cellulose antibacterial material with lysine grafted N-halamine type Schiff base structure and preparation method thereof | 长春工业大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-113943377-A | Cellulose antibacterial material with lysine grafted N-halamine type Schiff base structure and preparation method thereof | 长春工业大学 | 2022-01-18 | — | — | CN | disclosed |
| EP-1831207-B1 | AMINOPYRIMIDINE COMPOUNDS AS PLK INHIBITORS | AMGEN INC (US) | 2012-11-14 | — | — | EP | disclosed |
| US-7858785-B2 | Aminopyrimidine compounds and methods of use | AMGEN INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-7786132-B2 | Aminopyrimidine compounds and methods of use | AMGEN INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-20100010014-A1 | AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2010-01-14 | — | — | US | disclosed |
| EP-1831207-A1 | AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2007-09-12 | — | — | EP | disclosed |
| US-20070185133-A1 | Aminopyrimidine compounds and methods of use | AMGEN, INC. (US) | 2007-08-09 | — | — | US | disclosed |
| WO-2006066172-A1 | AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | AMGEN, INC. (US) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010014-A1 | AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | PLK1, TYMP, TK2 | POLB 16/4885AR 4251/4885 |
| US-20070185133-A1 | Aminopyrimidine compounds and methods of use | PLK1, TYMP, TK2 | POLB 16/4885AR 4251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.