Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.45 |
| ▸ | MC4R | P32245 | 4/20 | 0.42 |
| ▸ | MC3R | P41968 | 4/20 | 0.42 |
| ▸ | MC1R | Q01726 | 4/20 | 0.42 |
| ▸ | KLK7 | P49862 | 5/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1721741 | 0.89 | ABCB1 (0.58) | ABCB1BDKRB2KLK7JAK2JAK1 | |
| SCHEMBL30421652 | 0.89 | ABCB1 (0.58) | ABCB1BDKRB2KLK7JAK2JAK1 | |
| SCHEMBL7327353 | 0.87 | ABCB1 (0.58) | ABCB1BDKRB2KLK7JAK2JAK1 | |
| SCHEMBL28995867 | 0.87 | ABCB1 (0.58) | ABCB1BDKRB2KLK7JAK2JAK1 | |
| SCHEMBL14457250 | 0.87 | ABCB1 (0.58) | ABCB1BDKRB2KLK7JAK2JAK1 | |
| SCHEMBL30421047 | 0.87 | ABCB1 (0.58) | ABCB1BDKRB2KLK7JAK2JAK1 | |
| SCHEMBL475540 | 0.87 | ABCB1 (0.58) | ABCB1BDKRB2KLK7JAK2JAK1 | |
| SCHEMBL71548 | 0.87 | ABCB1 (0.58) | ABCB1BDKRB2KLK7JAK2JAK1 | |
| SCHEMBL3855580 | 0.87 | ABCB1 (0.58) | ABCB1BDKRB2KLK7JAK2JAK1 | |
| SCHEMBL24739417 | 0.86 | ABCB1 (0.54) | ABCB1BDKRB2KLK7JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1950198-B1 | PROCESS FOR PRODUCTION OF BENZYLOXYPYRROLIDINE DERIVATIVE, AND PROCESS FOR PRODUCTION OF HYDROCHLORIDE SALT POWDER OF OPTICALLY ACTIVE BENZYLOXYPYRROLIDINE DERIVATIVE | TORAY FINECHEMICALS CO LTD (JP) | 2014-08-06 | — | — | EP | disclosed |
| US-7772406-B2 | Process for production of benzyloxypyrrolidine derivative, and process for production of hydrochloride salt powder of optically active benzyloxypyrrolidine derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| US-20090093643-A1 | Process for Production of Benzyloxypyrrolidine Derivative, and Process for Production of Hydrochloride Salt Powder of Optically Active Benzyloxypyrrolidine Derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2009-04-09 | — | — | US | disclosed |
| EP-1950198-A1 | PROCESS FOR PRODUCTION OF BENZYLOXYPYRROLIDINE DERIVATIVE, AND PROCESS FOR PRODUCTION OF HYDROCHLORIDE SALT POWDER OF OPTICALLY ACTIVE BENZYLOXYPYRROLIDINE DERIVATIVE | Toray Fine Chemicals Co., Ltd. (JP) | 2008-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093643-A1 | Process for Production of Benzyloxypyrrolidine Derivative, and Process for Production of Hydrochloride Salt Powder of Optically Active Benzyloxypyrrolidine Derivative | HPD, PAH, DHPS | ABCB1 1026/4885BDKRB2 2432/4885MC4R 2686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.