Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27956715 | 0.81 | ACE2 (0.46) | TP53ACE2OPRM1CA1ZDHHC7 | |
| Ammonia Solution, Strong SCHEMBL27758035 | 0.79 | ACE2 (0.44) | TP53ACE2OPRM1CA1ZDHHC7 | |
| SCHEMBL27268372 | 0.77 | ACE2 (0.48) | TP53ACE2OPRM1CA1ADH1B | |
| SCHEMBL2236544 | 0.77 | TP53 (0.47) | TP53ACE2OPRM1CA1ADH1B | |
| SCHEMBL8812271 | 0.77 | TP53 (0.47) | TP53ACE2OPRM1CA1ADH1B | |
| SCHEMBL28854459 | 0.77 | SPHK1 (0.42) | TP53ZDHHC7SMPD1GPR84 | |
| SCHEMBL15353083 | 0.76 | CA1 (0.31) | CA1CA2CA9 | |
| SCHEMBL28405271 | 0.76 | GPR84 (0.46) | TP53ZDHHC7GPR84 | |
| SCHEMBL29043313 | 0.76 | GPR84 (0.46) | TP53ZDHHC7GPR84 | |
| SCHEMBL8812277 | 0.75 | TP53 (0.55) | TP53ACE2OPRM1CA1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114828959-B | 3- (5-methoxy-1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivative and application thereof | 诺华股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-114828959-A | 3- (5-methoxy-1-oxoisoindolin-2-yl) piperidine-2, 6-dione derivatives and uses thereof | 诺华股份有限公司 | 2022-07-29 | — | — | CN | disclosed |