Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARL | Q9H300 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | CCR6 | P51684 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RGS4 | P49798 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63108 | 0.89 | MAPT (0.44) | PARLPTGS2MAPTALDH1A1GAA | |
| SCHEMBL22251877 | 0.78 | PARL (0.68) | PARLMAPTALDH1A1GAACCR6 | |
| SCHEMBL11892735 | 0.76 | MAPT (0.57) | PARLMAPTALDH1A1GAACCR6 | |
| SCHEMBL64591 | 0.75 | PARL (0.42) | PARLPTGS2ALDH1A1GAAALOX12 | |
| Benzene SCHEMBL28164184 | 0.73 | PARL (0.60) | PARLPTGS2MAPTALDH1A1GAA | |
| SCHEMBL2980560 | 0.73 | MAPT (0.40) | PARLPTGS2MAPTALDH1A1GAA | |
| SCHEMBL152124 | 0.71 | MAPT (0.49) | MAPTALDH1A1GAACCR6NPSR1 | |
| SCHEMBL27755376 | 0.70 | MAPT (0.40) | PARLMAPTALDH1A1GAACCR6 | |
| SCHEMBL8607338 | 0.69 | MAPT (0.44) | MAPTALDH1A1GAACCR6NPSR1 | |
| SCHEMBL64828 | 0.68 | PARL (0.50) | PARLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE41580-E1 | Lactone-containing compounds, polymers, resist compositions, and patterning method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-08-24 | — | — | US | disclosed |