SCHEMBL8607338

SCHEMBL8607338

CC(=O)ON1C(=O)C=C(c2ccccc2)C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.44
ALDH1A1 P00352 4/20 0.44
NPSR1 Q6W5P4 3/20 0.44
HPGD P15428 3/20 0.44
GAA P10253 2/20 0.44
CCR6 P51684 2/20 0.44
ALOX12 P18054 2/20 0.44
CACNA1B Q00975 2/20 0.44
APBA1 Q02410 2/20 0.44
LMNA P02545 4/20 0.42
HTT P42858 1/20 0.42
RGS4 P49798 1/20 0.39
DRD2 P14416 1/20 0.37
DRD3 P35462 1/20 0.37
HCRTR1 O43613 1/20 0.36
S1PR4 O95977 1/20 0.36
HSP90AA1 P07900 1/20 0.36
S1PR1 P21453 1/20 0.36
BACE1 P56817 3/20 0.35
FOS P01100 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL152124 0.80 MAPT (0.49) MAPTALDH1A1NPSR1HPGDGAA
SCHEMBL63108 0.77 MAPT (0.44) MAPTALDH1A1NPSR1HPGDGAA
SCHEMBL9435961 0.76 ALDH1A1 (0.40) MAPTALDH1A1NPSR1HPGDGAA
SCHEMBL3691136 0.75 MAPT (0.45) MAPTALDH1A1NPSR1HPGDGAA
SCHEMBL10834531 0.75 MAPT (0.45) MAPTALDH1A1NPSR1HPGDGAA
SCHEMBL9418787 0.75 MAPT (0.42) MAPTALDH1A1NPSR1HPGDGAA
SCHEMBL9240802 0.75 MAPT (0.47) MAPTALDH1A1NPSR1HPGDGAA
SCHEMBL6740675 0.75 MAPT (0.47) MAPTALDH1A1NPSR1HPGDGAA
SCHEMBL28770983 0.72 MAPT (0.45) MAPTALDH1A1NPSR1HPGDGAA
SCHEMBL8568470 0.72 MAPT (0.45) MAPTALDH1A1NPSR1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0202498-B1 USE OF A THERMO-SETTING, POLYMERIZABLE COMPOSITION AND WIRING BOARD HITACHI, LTD. (JP) 1990-07-11 EP claimed
EP-0202498-A2 Use of a thermo-setting, polymerizable composition and wiring board HITACHI, LTD. (JP) 1986-11-26 EP claimed
EP-0720060-B1 Process for the development of irradiated radiation-sensitive recording materials AGFA GEVAERT AG (DE) 1998-03-25 EP disclosed
EP-0720060-A1 Process for the development of irradiated radiation-sensitive recording materials HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-03 EP disclosed
EP-0315211-B1 Thermosetting resin composition, and prepreg and laminated sheet which use the same HITACHI LTD (JP) 1995-05-24 EP disclosed
US-5212244-A Heat and fire resistance, dimensional stability, printed circuits HITACHI, LTD. (JP) 1993-05-18 US disclosed
US-5080965-A PREPREG FROM POLY(P-HYDROXYSTYRENE), EPOXY-MODIFIED POLYBUTADIENE AND MALEIMIDE HITACHI, LTD. (JP) 1992-01-14 US disclosed
EP-0269021-B1 RESIN COMPOSITION FOR PRINTED CIRCUIT BOARD AND SUCH BOARD FORMED BY USE THEREOF HITACHI, LTD. (JP) 1991-10-23 EP disclosed
US-5041478-A Maleimidized cyclic phosphonitrile with an aromatic amine and/or aromatic maleimide; heat resistant, moisture resistant HITACHI, LTD. (JP) 1991-08-20 US disclosed
US-4946734-A MALEIMIDE SUBSTITUTED PHOSPHONITRILE HITACHI, LTD. (JP) 1990-08-07 US disclosed
EP-0202498-B1 USE OF A THERMO-SETTING, POLYMERIZABLE COMPOSITION AND WIRING BOARD HITACHI, LTD. (JP) 1990-07-11 EP disclosed
EP-0315211-A1 Thermosetting resin composition, and prepreg and laminated sheet which use the same HITACHI, LTD. (JP) 1989-05-10 EP disclosed
US-4738900-A HEAT RESISTANT DIELECTRIC LAYER OF A POLYMER OF AN AROMATIC DIMALEIMIDE AND AN AROMATIC DICYANAMIDE HITACHI, LTD. (JP) 1988-04-19 US disclosed
EP-0202498-A2 Use of a thermo-setting, polymerizable composition and wiring board HITACHI, LTD. (JP) 1986-11-26 EP disclosed
EP-0078039-B1 THERMOSETTING RESIN COMPOSITION, PREPOLYMER THEREOF AND CURED ARTICLE THEREOF Hitachi, Ltd. (JP) 1986-01-22 EP disclosed
US-4546168-A POLYMERIZABLE EPOXY COMPOUNDS, PHENOLIC COMPOUNDS, AND TRIALLYL ISOCYANURATE COMPOUNDS HITACHI, LTD. (JP) 1985-10-08 US disclosed
US-4482703-A Thermosetting resin composition comprising dicyanamide and polyvalent imide HITACHI, LTD. (JP) 1984-11-13 US disclosed
EP-0123262-A2 Resin encapsulated semiconductor device and process for producing the same HITACHI, LTD. (JP) 1984-10-31 EP disclosed
US-4400438-A MALEIMIDE RESING AND HALOGENATED DIPHENYL ETHER HITACHI CHEMICAL COMPANY, LTD. (JP) 1983-08-23 US disclosed
EP-0078039-A1 Thermosetting resin composition, prepolymer thereof and cured article thereof Hitachi, Ltd. (JP) 1983-05-04 EP disclosed