SCHEMBL29807

SCHEMBL29807

CN(CBr)CCOC(c1ccccc1)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 7/20 0.69
SLC6A4 P31645 7/20 0.69
SLC6A3 Q01959 7/20 0.69
LMNA P02545 3/20 0.69
CHRM2 P08172 3/20 0.69
ADRA2A P08913 3/20 0.69
CHRM1 P11229 3/20 0.69
OPRM1 P35372 3/20 0.69
DRD3 P35462 3/20 0.69
CYP2D6 P10635 3/20 0.69
SCN1A P35498 3/20 0.69
SCN2A Q99250 3/20 0.69
SCN3A Q9NY46 3/20 0.69
CHRM4 P08173 2/20 0.69
CHRM5 P08912 2/20 0.69
ADRA2B P18089 2/20 0.69
CHRM3 P20309 2/20 0.69
HRH2 P25021 2/20 0.69
HTR2A P28223 2/20 0.69
HTR2C P28335 2/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL141832 0.98 LMNA (0.70) SLC6A2SLC6A4SLC6A3LMNACHRM2
SCHEMBL2553732 0.84 SLC6A2 (0.71) SLC6A2SLC6A4SLC6A3LMNACHRM2
SCHEMBL9173563 0.83 SLC6A2 (0.69) SLC6A2SLC6A4SLC6A3LMNACHRM2
SCHEMBL11795338 0.83 SLC6A2 (0.69) SLC6A2SLC6A4SLC6A3LMNACHRM2
SCHEMBL13302844 0.83 SIGMAR1 (0.69) SLC6A2SLC6A4SLC6A3LMNACHRM2
Diphenhydramine SCHEMBL141881 0.82 SLC6A2 (0.93) SLC6A2SLC6A4SLC6A3LMNACHRM2
Diphenhydramine SCHEMBL4064 0.82 SLC6A2 (1.00) SLC6A2SLC6A4SLC6A3LMNACHRM2
Diphenhydramine SCHEMBL12543374 0.82 SLC6A2 (1.00) SLC6A2SLC6A4SLC6A3LMNACHRM2
SCHEMBL16590605 0.81 SIGMAR1 (0.68) SLC6A2SLC6A4SLC6A3LMNACHRM2
SCHEMBL16590608 0.81 SIGMAR1 (0.68) SLC6A2SLC6A4SLC6A3LMNACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2531 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630401-A2 CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF Rutgers, the State University of New Jersey (US) 2025-10-15 EP claimed
US-20250177398-A1 CARBONIC ANHYDRASE ENZYMES FOR REGULATING MAST CELL HEMATOPOIESIS AND TYPE 2 INFLAMMATION RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2025-06-05 US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
US-12263168-B2 Carbonic anhydrase enzymes for regulating mast cell hematopoiesis and type 2 inflammation RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2025-04-01 US claimed
US-20250099498-A1 STRONTIUM BASED COMPOSITIONS AND FORMULATIONS FOR PAIN, PRURITUS, AND INFLAMMATION GALLEON LABS LLC (US) 2025-03-27 US claimed
US-12251469-B2 Sterically stabilized carrier compositions for treating a mammal VGSK TECHNOLOGIES, INC. (US) 2025-03-18 US claimed
US-20240415789-A1 CYCLOBENZAPRINE FOR TREATMENT OR PREVENTION OF SEXUAL DYSFUNCTION ASSOCIATED WITH MENTAL HEALTH CONDITIONS IN FEMALE PATIENTS TONIX PHARMA LIMITED (IE) 2024-12-19 US claimed
US-20240390364-A1 Novel Pyridine Compositions and their use in methods for preventing or treating diseases, disorders and conditions REID CHRISTOPHER BRIAN (US) 2024-11-28 US claimed
US-12121536-B2 Strontium based compositions and formulations for pain, pruritus, and inflammation GALLEON LABS LLC (US) 2024-10-22 US claimed
US-20240299292-A1 STABLE SEMI-SOLID CHEWABLE GEL COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF SEATTLE GUMMY COMPANY (US) 2024-09-12 US claimed
US-5025019-A Sympathomimetic amines antihistamines for oral administration to mammals ANALGESIC ASSOCIATES (US) 1991-06-18 US claimed
US-4996047-A Sustained release drug-resin complexes RICHARDSON-VICKS, INC. (US) 1991-02-26 US claimed
EP-0367746-A2 Sustained release drug-resin complexes RICHARDSON-VICKS, INC. (US) 1990-05-09 EP claimed
US-4840962-A MIXTURE WITH ANTIHISTAMINE, DECONGESTANT AND/OR ANTITUSSIVE AGENT ANALGESIC ASSOCIATES (US) 1989-06-20 US claimed
US-4749720-A ANALGESICS AND ANTIHISTAMINES ANALGESIC ASSOCIATES (US) 1988-06-07 US claimed
US-4749697-A ADMINISTERING MIXTURES OF PIROXICAM, SUDOXICAM, OR ISOXICAM WITH ANTIHISTAMINE ANALGESIC ASSOCIATES (US) 1988-06-07 US claimed
US-4749723-A ADMINISTERING MEFENAMIC ACID, SODIUM MECLOFENAMATE OR SALT WITH ANTIHISTAMINE ANALGESIC ASSOCIATES (US) 1988-06-07 US claimed
US-4619934-A AND ANTIHISTAMINE, DECONGESTANT, ANTITUSSIVE OR EXPECTORANT ANALGESIC ASSOCIATES (US) 1986-10-28 US claimed
US-4104382-A (((THIAZOLYL-, ISOTHIAZOLYL- OR PYRIDYLALKYL)THIO)ALKYL)GUANIDINE SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1978-08-01 US claimed
US-4000302-A ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1976-12-28 US claimed