SCHEMBL29808604

SCHEMBL29808604

O=C(c1ccc2ccccc2c1)n1ccc2ccc(Cl)cc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
RAB9A P51151 3/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
OXER1 Q8TDS5 1/20 0.49
POLH Q9Y253 1/20 0.47
BCHE P06276 1/20 0.46
ENPP3 O14638 1/20 0.45
ALPL P05186 1/20 0.45
XIAP P98170 1/20 0.45
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
CYP2A6 P11509 1/20 0.44
NPC1 O15118 3/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HPGD P15428 1/20 0.43
KMO O15229 1/20 0.43
AKR1C1 Q04828 1/20 0.43
SLC22A12 Q96S37 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31435524 0.86 TSHR (0.70) TSHRRAB9AL3MBTL1BCHEENPP3
SCHEMBL6587897 0.80 RAB9A (0.75) TSHRRAB9AL3MBTL1CES2CES1
SCHEMBL22956030 0.78 OXER1 (0.50) TSHRRAB9AL3MBTL1OXER1BCHE
SCHEMBL28389492 0.75 OXER1 (0.47) TSHRL3MBTL1OXER1KMT2AKMO
SCHEMBL28661724 0.75 OXER1 (0.63) TSHRRAB9AL3MBTL1OXER1KMO
SCHEMBL31435522 0.75 RAB9A (0.66) TSHRRAB9AL3MBTL1OXER1BCHE
SCHEMBL23360817 0.73 NOTUM (0.58) OXER1HPGDKMO
SCHEMBL22955291 0.72 OXER1 (0.44) TSHRRAB9AL3MBTL1OXER1NPC1
SCHEMBL22147535 0.72 BCHE (0.80) BCHEMEN1KMT2AHPGD
SCHEMBL29936818 0.70 TSHR (0.51) TSHRRAB9AL3MBTL1OXER1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125348-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS OREGON STATE UNIVERSITY (US) 2026-05-07 US disclosed
EP-4710922-A2 ARYL HYDROCARBON RECEPTOR ACTIVATORS Oregon State University (US) 2026-03-18 EP disclosed
EP-4003337-B1 ARYL HYDROCARBON RECEPTOR ACTIVATORS UNIV OREGON STATE (US) 2026-03-11 EP disclosed
US-12473262-B2 Aryl hydrocarbon receptor activators OREGON STATE UNIVERSITY (US) 2025-11-18 US disclosed
US-20220281824-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS OREGON STATE UNIVERSITY (US) 2022-09-08 US disclosed
EP-4003337-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS Oregon State University (US) 2022-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220281824-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS AHR, ARNT, NR0B1 TSHR 40/4885RAB9A 3686/4885L3MBTL1 1457/4885
US-20260125348-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS AHR, ARNT, NR1H2 TSHR 13/4885RAB9A 2472/4885L3MBTL1 915/4885
US-12473262-B2 Aryl hydrocarbon receptor activators AHR, ARNT, NR0B1 TSHR 40/4885RAB9A 3686/4885L3MBTL1 1457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.