Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 5/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24466985 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL24467002 | 0.90 | KMT2A (0.46) | SMN1; SMN2MAPTNPC1RAB9APKM | |
| SCHEMBL29808793 | 0.90 | KMT2A (0.46) | SMN1; SMN2MAPTNPC1RAB9APKM | |
| SCHEMBL29808686 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTNPC1RAB9APKM | |
| SCHEMBL24467020 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTNPC1RAB9APKM | |
| SCHEMBL24466948 | 0.88 | MAPT (0.42) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL29714957 | 0.88 | MAPT (0.42) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL24466915 | 0.88 | ALDH1A1 (0.47) | SMN1; SMN2MAPTL3MBTL1PKMALDH1A1 | |
| SCHEMBL24466980 | 0.88 | LSS (0.46) | SMN1; SMN2MAPTL3MBTL1PKMKMT2A | |
| SCHEMBL24466964 | 0.87 | MAPT (0.43) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006037-A1 | HETEROCYCLIC COMPOUND | Fimecs, Inc. (JP) | 2022-06-01 | — | — | EP | claimed |
| EP-4006037-A1 | HETEROCYCLIC COMPOUND | Fimecs, Inc. (JP) | 2022-06-01 | — | — | EP | disclosed |