Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24466915 | 0.90 | ALDH1A1 (0.47) | TP53KMT2APKMMAPTSMN1; SMN2 | |
| SCHEMBL29714957 | 0.90 | MAPT (0.42) | MAPTSMN1; SMN2GPR119CNR1CNR2 | |
| SCHEMBL29808793 | 0.90 | KMT2A (0.46) | KMT2APKMMAPTSMN1; SMN2GPR119 | |
| SCHEMBL24466948 | 0.90 | MAPT (0.42) | MAPTSMN1; SMN2GPR119CNR1CNR2 | |
| SCHEMBL24467002 | 0.90 | KMT2A (0.46) | KMT2APKMMAPTSMN1; SMN2GPR119 | |
| SCHEMBL24467042 | 0.88 | SMN1; SMN2 (0.54) | TP53KMT2APKMSMN1; SMN2SCN1A | |
| SCHEMBL29808613 | 0.88 | SMN1; SMN2 (0.60) | KMT2APKMMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL24466985 | 0.88 | SMN1; SMN2 (0.60) | KMT2APKMMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL24466951 | 0.84 | PKM (0.44) | KMT2APKMSMN1; SMN2GPR119FPR2 | |
| SCHEMBL29808682 | 0.84 | PKM (0.44) | KMT2APKMSMN1; SMN2GPR119FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402935-A1 | HETEROCYCLIC COMPOUND | FIMECS, INC. (JP) | 2022-12-22 | — | — | US | disclosed |
| EP-4006037-A1 | HETEROCYCLIC COMPOUND | Fimecs, Inc. (JP) | 2022-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402935-A1 | HETEROCYCLIC COMPOUND | IRAK1, IRAK2, IRAK4 | LSS 3533/4885TP53 792/4885HTR2B 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.