Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24733512 | 1.00 | ACP1 (0.45) | ACP1KDM4EALDH1A1GLAGAA | |
| SCHEMBL29809097 | 0.93 | FABP4 (0.44) | ACP1ALDH1A1HPGDBCHEHRH3 | |
| SCHEMBL24733118 | 0.93 | FABP4 (0.44) | ACP1ALDH1A1HPGDBCHEHRH3 | |
| SCHEMBL24732883 | 0.87 | TLR7 (0.46) | ACP1BCHETLR7 | |
| SCHEMBL28802673 | 0.87 | TLR7 (0.47) | ACP1BCHEHRH3FABP4TLR7 | |
| SCHEMBL29977565 | 0.87 | ACP1 (0.44) | ACP1BCHEHRH3FABP4TLR7 | |
| SCHEMBL27213640 | 0.86 | ACP1 (0.47) | ACP1BCHEFABP4TLR7SIGMAR1 | |
| SCHEMBL24733063 | 0.84 | ACP1 (0.45) | ACP1BCHETLR7SIGMAR1SSTR5 | |
| SCHEMBL29809309 | 0.84 | ACP1 (0.45) | ACP1BCHETLR7SIGMAR1SSTR5 | |
| SCHEMBL27213644 | 0.84 | TLR7 (0.47) | ACP1BCHEFABP4TLR7SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805341-B | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114805341-A | Aromatic heterocyclic compounds and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |