SCHEMBL29977565 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	ACP1	P24666	5/20	0.44

▸	TLR7	Q9NYK1	1/20	0.42

▸	CXCR4	P61073	2/20	0.41

▸	SIGMAR1	Q99720	1/20	0.41

▸	RAB9A	P51151	1/20	0.40

▸	CYP1A2	P05177	1/20	0.39

▸	CYP2C19	P33261	1/20	0.39

▸	BCHE	P06276	1/20	0.39

▸	LMNA	P02545	1/20	0.39

▸	HTR1A	P08908	1/20	0.39

▸	HTR1D	P28221	1/20	0.39

▸	HTR1B	P28222	1/20	0.39

▸	SSTR5	P35346	1/20	0.39

▸	FABP4	P15090	1/20	0.39

▸	HRH3	Q9Y5N1	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL27213640	0.88	ACP1 (0.47)	ACP1TLR7SIGMAR1RAB9ABCHE
SCHEMBL24733512	0.87	ACP1 (0.45)	ACP1TLR7SIGMAR1BCHESSTR5
SCHEMBL29808964	0.87	ACP1 (0.45)	ACP1TLR7SIGMAR1BCHESSTR5
SCHEMBL29809097	0.86	FABP4 (0.44)	ACP1TLR7SIGMAR1RAB9ABCHE
SCHEMBL24733118	0.86	FABP4 (0.44)	ACP1TLR7SIGMAR1RAB9ABCHE
SCHEMBL29809309	0.85	ACP1 (0.45)	ACP1TLR7SIGMAR1RAB9ABCHE
SCHEMBL24733063	0.85	ACP1 (0.45)	ACP1TLR7SIGMAR1RAB9ABCHE
SCHEMBL27213644	0.85	TLR7 (0.47)	ACP1TLR7SIGMAR1RAB9ABCHE
SCHEMBL28802673	0.85	TLR7 (0.47)	ACP1TLR7SIGMAR1BCHEFABP4
SCHEMBL24732883	0.84	TLR7 (0.46)	ACP1TLR7BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022161420-A1	CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF	上海翊石医药科技有限公司	2022-08-04	—	—	WO	disclosed