Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424115 | 1.00 | L3MBTL1 (0.54) | L3MBTL1FAAHHCRTR1HCRTR2ACACB | |
| SCHEMBL20505562 | 0.82 | ACACB (0.60) | L3MBTL1ACACBGRM2CYP19A1CDC7 | |
| SCHEMBL7359643 | 0.82 | CYP19A1 (0.52) | L3MBTL1FAAHHCRTR1HCRTR2SIRT2 | |
| SCHEMBL3906515 | 0.82 | SLC6A2 (0.47) | L3MBTL1FAAHHCRTR1HCRTR2SIRT2 | |
| Hydrochloric Acid SCHEMBL6886546 | 0.81 | SLC6A2 (0.46) | L3MBTL1FAAHHCRTR1HCRTR2SIRT2 | |
| SCHEMBL26357090 | 0.79 | POLB (0.64) | L3MBTL1FAAHHCRTR1HCRTR2SIRT2 | |
| SCHEMBL20576177 | 0.79 | L3MBTL1 (0.64) | L3MBTL1ACACBGRM2CYP19A1HRH3 | |
| SCHEMBL24732719 | 0.78 | L3MBTL1 (0.58) | L3MBTL1ACACBCDC7PLK4AURKA | |
| SCHEMBL13181473 | 0.78 | L3MBTL1 (0.58) | L3MBTL1ACACBALOX5CDC7PLK4 | |
| SCHEMBL8327744 | 0.78 | KMT2A (0.61) | L3MBTL1ACACBCDC7PLK4AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805341-B | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114805341-A | Aromatic heterocyclic compounds and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |