Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CHKA | P35790 | 2/20 | 0.52 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24732674 | 1.00 | POLB (0.56) | POLBPRMT6SMN1; SMN2CHKACYP2A13 | |
| SCHEMBL29809073 | 0.87 | PRMT6 (0.56) | POLBPRMT6SMN1; SMN2CHKAALDH1A1 | |
| SCHEMBL24732648 | 0.87 | PRMT6 (0.56) | POLBPRMT6SMN1; SMN2CHKAALDH1A1 | |
| SCHEMBL29808844 | 0.80 | PRMT6 (0.56) | PRMT6SMN1; SMN2CHKAALDH1A1KDM4E | |
| SCHEMBL24732909 | 0.80 | PRMT6 (0.56) | PRMT6SMN1; SMN2CHKAALDH1A1KDM4E | |
| SCHEMBL1934178 | 0.80 | KDM4E (0.63) | PRMT6SMN1; SMN2CHKAALDH1A1KDM4E | |
| SCHEMBL2208032 | 0.79 | ACHE (0.60) | POLBSMN1; SMN2CHKACYP2A13ALDH1A1 | |
| SCHEMBL24508364 | 0.79 | KDM4E (0.73) | POLBSMN1; SMN2CYP2A13ALDH1A1KDM4E | |
| SCHEMBL3859176 | 0.78 | ACHE (0.58) | POLBSMN1; SMN2CHKACYP2A13ALDH1A1 | |
| SCHEMBL111330 | 0.78 | HRH3 (0.74) | POLBPRMT6SMN1; SMN2CHKAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805341-B | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114805341-A | Aromatic heterocyclic compounds and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |