Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501106 | 0.80 | LMNA (0.50) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL27610347 | 0.79 | LMNA (0.43) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL27663277 | 0.79 | LMNA (0.43) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL8373989 | 0.71 | LMNA (0.46) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL18285214 | 0.71 | LMNA (0.46) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL7520052 | 0.71 | LMNA (0.46) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL8377780 | 0.71 | LMNA (0.46) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL9326932 | 0.70 | LMNA (0.50) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL9748371 | 0.70 | LMNA (0.50) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL8825280 | 0.70 | LMNA (0.50) | LMNAL3MBTL1TDP1USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108707140-B | Protease C inhibitors | 勃林格殷格翰国际有限公司 | 2022-07-22 | — | — | CN | disclosed |