Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23832310 | 1.00 | MAP3K14 (0.42) | MAP3K14ADRA2AOPRL1NPC1RAB9A | |
| SCHEMBL3269304 | 1.00 | MAP3K14 (0.42) | MAP3K14ADRA2AOPRL1NPC1RAB9A | |
| SCHEMBL29846494 | 1.00 | MAP3K14 (0.42) | MAP3K14ADRA2AOPRL1NPC1RAB9A | |
| SCHEMBL28575567 | 1.00 | MAP3K14 (0.42) | MAP3K14ADRA2AOPRL1NPC1RAB9A | |
| SCHEMBL29848515 | 1.00 | MAP3K14 (0.42) | MAP3K14ADRA2AOPRL1NPC1RAB9A | |
| Acetic Acid SCHEMBL28839973 | 0.91 | MAP3K14 (0.40) | MAP3K14OPRL1NPC1RAB9A | |
| Acetic Acid SCHEMBL28839975 | 0.91 | MAP3K14 (0.40) | MAP3K14OPRL1NPC1RAB9A | |
| SCHEMBL4732629 | 0.80 | ADRA2A (0.32) | ADRA2AOPRL1 | |
| SCHEMBL3562075 | 0.80 | ADRA2A (0.32) | MAP3K14ADRA2A | |
| SCHEMBL28418993 | 0.80 | ADRA2A (0.32) | MAP3K14ADRA2AOPRL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527272-B | Synthetic method of tergolian prazan | 西安淳甄新材料有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-114907303-A | Preparation method of chiral chromanol of tegorazalol intermediate | 常州工程职业技术学院 | 2022-08-16 | — | — | CN | claimed |
| CN-114805317-A | Preparation method of Tegolrazan | 江苏威奇达药业有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-118599794-A | Carbonyl reductase mutant and application thereof in synthesis of agoraphobia intermediate | 杭州文德阶生物科技有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-115108994-B | Tergolian intermediate and preparation method and application thereof | 江苏威奇达药业有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-117024417-A | Preparation method of terglazan | 上海柏狮生物科技有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-113527272-B | Synthetic method of tergolian prazan | 西安淳甄新材料有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-116375650-A | Preparation method of agoraphobia intermediate | 浙江美诺华药物化学有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-112851646-B | Preparation method of tergolian prazan | 中国医学科学院药物研究所 | 2023-06-13 | — | — | CN | disclosed |
| CN-115108994-A | Tegolrazan intermediate and preparation method and application thereof | 江苏威奇达药业有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-114907303-A | Preparation method of chiral chromanol of tegorazalol intermediate | 常州工程职业技术学院 | 2022-08-16 | — | — | CN | disclosed |
| CN-114874187-A | Preparation method of vitacoxib | 江苏慧聚药业股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114805317-A | Preparation method of Tegolrazan | 江苏威奇达药业有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805317-A | Preparation method of Tegolrazan | 江苏威奇达药业有限公司 | 2022-07-29 | — | — | CN | disclosed |