Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5263685 | 0.80 | MAPT (0.40) | MAPTALDH1A1MEN1APAF1HPGD | |
| SCHEMBL9221467 | 0.74 | NR3C1 (0.44) | MAPTALDH1A1MEN1APAF1HPGD | |
| SCHEMBL29630944 | 0.66 | KMT2A (0.60) | MAPTALDH1A1MEN1APAF1HPGD | |
| SCHEMBL1466305 | 0.66 | KMT2A (0.60) | MAPTALDH1A1MEN1APAF1HPGD | |
| SCHEMBL20060315 | 0.66 | NR3C1 (0.45) | MAPTALDH1A1MEN1APAF1HPGD | |
| SCHEMBL1127776 | 0.66 | HDAC3 (0.46) | MAPTALDH1A1MEN1APAF1HPGD | |
| SCHEMBL18176034 | 0.66 | NR3C1 (0.58) | MAPTALDH1A1MEN1APAF1HPGD | |
| SCHEMBL11537037 | 0.66 | SIGMAR1 (0.39) | MAPTALDH1A1MEN1APAF1HPGD | |
| Hydrochloric Acid SCHEMBL8870700 | 0.64 | HDAC3 (0.45) | MAPTALDH1A1MEN1APAF1HPGD | |
| Bromide SCHEMBL3601831 | 0.64 | HDAC3 (0.45) | MAPTALDH1A1MEN1APAF1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805204-B | Method for preparing 4-iodoisoquinoline-1 (2H) -ketone compound | 云南师范大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-114805204-A | Method for preparing 4-iodoisoquinoline-1 (2H) -ketone compound | 云南师范大学 | 2022-07-29 | — | — | CN | disclosed |