Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MB | P02144 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640443 | 1.00 | PDE3B (0.58) | PDE3BPDE3ACYP11B1CYP11B2CA9 | |
| SCHEMBL31491338 | 0.85 | CA9 (0.56) | PDE3BPDE3ACYP11B1CYP11B2CA9 | |
| SCHEMBL3598259 | 0.85 | CA9 (0.56) | PDE3BPDE3ACYP11B1CYP11B2CA9 | |
| SCHEMBL6371439 | 0.82 | CA9 (0.45) | PDE3BPDE3ACYP11B1CYP11B2CA9 | |
| SCHEMBL2061036 | 0.79 | CA9 (0.43) | PDE3BPDE3ACA9GAAMAPT | |
| SCHEMBL8551799 | 0.78 | PDE3B (0.58) | PDE3BPDE3ACYP11B1CYP11B2MAPK1 | |
| SCHEMBL13496007 | 0.78 | PDE3B (0.58) | PDE3BPDE3ACYP11B1CYP11B2CA9 | |
| SCHEMBL29546522 | 0.78 | PDE3B (0.58) | PDE3BPDE3ACYP11B1CYP11B2CA9 | |
| SCHEMBL429197 | 0.78 | PDE3B (0.58) | PDE3BPDE3ACYP11B1CYP11B2CA9 | |
| SCHEMBL3640442 | 0.78 | PDE3B (0.58) | PDE3BPDE3ACYP11B1CYP11B2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278816-B | Dihydro quinolinones | C4医药公司 | 2024-03-15 | — | — | CN | disclosed |
| US-11401256-B2 | Dihydroquinolinones for medical treatment | C4 THERAPEUTICS, INC. (US) | 2022-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11401256-B2 | Dihydroquinolinones for medical treatment | CRBN, RBX1, ADRM1 | PDE3B 4238/4885PDE3A 4254/4885CYP11B1 2498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.