SCHEMBL29811050

SCHEMBL29811050

CC[C@H](C)[C@H](N)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)O)[C@@H](C)O)[C@@H](C)CC

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ NPY2R P49146 8/20 0.68
▸ NPY4R P50391 8/20 0.68
▸ NPY5R Q15761 8/20 0.68
▸ NPY1R P25929 6/20 0.68
▸ CALCR P30988 6/20 0.64
▸ HCRTR1 O43613 1/20 0.64
▸ HCRTR2 O43614 1/20 0.64
▸ RAMP3 O60896 2/20 0.63
▸ GLP1R P43220 1/20 0.62
▸ RAMP1 O60894 1/20 0.60
▸ RAMP2 O60895 1/20 0.60
▸ CALCRL Q16602 1/20 0.60
▸ F2 P00734 1/20 0.60
▸ CRHR1 P34998 1/20 0.59
▸ CRHR2 Q13324 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29836372 0.90 C5AR1 (0.63) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30495758 0.90 CALCR (0.72) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30495635 0.89 NPY2R (0.66) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL13248707 0.89 NPY2R (0.80) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30511759 0.89 CALCR (0.66) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30262180 0.89 F2 (0.59) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL29903219 0.89 NPY2R (0.66) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL31182486 0.88 CALCR (0.69) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30431782 0.88 CALCR (0.65) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL31182812 0.88 NPY2R (0.65) NPY2RNPY4RNPY5RNPY1RCALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-08-10 — — US disclosed
US-20230066762-A1 IMMUNOGENIC COMPOSITION GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-03-02 — — US disclosed
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-09-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 NPY2R 2991/4885NPY4R 3062/4885NPY5R 3179/4885
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 NPY2R 2991/4885NPY4R 3062/4885NPY5R 3179/4885
US-20230066762-A1 IMMUNOGENIC COMPOSITION CXCL10, CCL2, CCL11 NPY2R 3202/4885NPY4R 3821/4885NPY5R 3232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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