SCHEMBL29811066

SCHEMBL29811066

CSCC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1)[C@@H](C)O)C(C)C)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 3/20 0.69
▸ NPY2R P49146 8/20 0.63
▸ NPY4R P50391 8/20 0.63
▸ NPY5R Q15761 8/20 0.63
▸ NPY1R P25929 6/20 0.63
▸ MAOB P27338 1/20 0.63
▸ KDM5A P29375 1/20 0.63
▸ KDM1B Q8NB78 1/20 0.63
▸ MAPK8 P45983 1/20 0.62
▸ MAPK9 P45984 1/20 0.62
▸ MAPK10 P53779 1/20 0.62
▸ TFPI P10646 6/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30903282 0.94 KDM1A (0.69) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL29461492 0.94 NPY2R (0.64) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL31182520 0.92 KDM1A (0.67) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL30262204 0.89 KDM1A (0.63) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL31182733 0.89 KDM1A (0.61) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL30262210 0.89 KDM1A (0.74) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL30737611 0.88 KDM1A (0.69) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL30737614 0.88 KDM1A (0.69) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL30737437 0.88 KDM1A (0.69) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL30737601 0.88 KDM1A (0.69) KDM1ANPY2RNPY4RNPY5RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-08-10 — — US disclosed
US-20230066762-A1 IMMUNOGENIC COMPOSITION GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-03-02 — — US disclosed
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-09-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 KDM1A 4837/4885NPY2R 2991/4885NPY4R 3062/4885
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 KDM1A 4837/4885NPY2R 2991/4885NPY4R 3062/4885
US-20230066762-A1 IMMUNOGENIC COMPOSITION CXCL10, CCL2, CCL11 KDM1A 4738/4885NPY2R 3202/4885NPY4R 3821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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