Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 9/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 7/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 4/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28346481 | 0.88 | MAP2K1 (0.40) | MAP2K1MAP2K2BRD4KDM4EIKBKB | |
| SCHEMBL29720980 | 0.84 | TGFBR1 (0.39) | KDM4ENPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL29812350 | 0.82 | IKBKB (0.41) | MAP2K1MAP2K2IKBKBMEN1JAK2 | |
| SCHEMBL29811076 | 0.80 | MAP2K1 (0.40) | MAP2K1MAP2K2BRD4KDM4EALDH1A1 | |
| SCHEMBL29812405 | 0.77 | MAP2K1 (0.35) | MAP2K1MAP2K2KDM4EIKBKBMEN1 | |
| SCHEMBL29811051 | 0.77 | POLB (0.40) | MAP2K1MAP2K2BRD4NPC1ALDH1A1 | |
| SCHEMBL29812100 | 0.77 | MAP2K2 (0.35) | MAP2K1MAP2K2IKBKBMEN1JAK2 | |
| SCHEMBL29720908 | 0.76 | GRIA2 (0.39) | MAP2K1MAP2K2ALDH1A1IKBKBMEN1 | |
| SCHEMBL29720900 | 0.74 | TGFBR1 (0.42) | IKBKBMEN1JAK2EIF2AK2KMT2A | |
| SCHEMBL29812363 | 0.74 | POLB (0.35) | MAP2K1MAP2K2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787144-A | Pyridone compounds and methods for modulating protein kinases | 埃克塞里艾克西斯公司 | 2022-07-22 | — | — | CN | disclosed |