Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20633526 | 1.00 | CA12 (0.35) | CA12CA9CA1CA2CNR2 | |
| SCHEMBL20633522 | 0.87 | CA12 (0.39) | CA12CA9CA1CA2CNR2 | |
| SCHEMBL18795101 | 0.84 | CNR2 (0.36) | CA12CA9CA1CA2CNR2 | |
| SCHEMBL29814270 | 0.84 | LMNA (0.49) | CA12CA9CA1CA2CNR2 | |
| SCHEMBL20633527 | 0.84 | LMNA (0.49) | CA12CA9CA1CA2CNR2 | |
| SCHEMBL17383389 | 0.84 | CA12 (0.37) | CA12CA9CA1CA2CNR2 | |
| SCHEMBL20632936 | 0.83 | UTRN (0.37) | NPC1RAB9ASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL29814439 | 0.83 | UTRN (0.37) | NPC1RAB9ASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL20633382 | 0.81 | PDE3B (0.33) | CA12CA9CA1CA2CNR2 | |
| SCHEMBL29814479 | 0.81 | PDE3B (0.33) | CA12CA9CA1CA2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649118-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2024-08-28 | — | — | EP | disclosed |
| US-11399542-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2022-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11399542-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | DDT, CHRM1, ACHE | CA12 4403/4885CA9 3967/4885CA1 1470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.