Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HNF4A | P41235 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29815326 | 0.89 | LCK (0.41) | PTPN1MMP1MMP2MMP9NR1H3 | |
| SCHEMBL29815053 | 0.83 | NFE2L2 (0.48) | KDM1ASNCAMMP9PTGS1MEN1 | |
| SCHEMBL29815013 | 0.83 | APP (0.35) | MMP1MMP2MMP9KMT2ANFE2L2 | |
| SCHEMBL29815035 | 0.83 | NFE2L2 (0.41) | PTGS1MEN1KMT2ANFE2L2 | |
| SCHEMBL28820816 | 0.80 | BCHE (0.39) | KDM1A | |
| SCHEMBL28820660 | 0.80 | BCHE (0.39) | KDM1A | |
| SCHEMBL29815022 | 0.78 | CYP19A1 (0.41) | KDM1ANQO2MEN1KMT2A | |
| SCHEMBL29814949 | 0.78 | ERBB2 (0.37) | — | |
| SCHEMBL29815123 | 0.78 | TRPA1 (0.41) | SIRT1PTPN1PTGS1 | |
| SCHEMBL31231848 | 0.76 | APP (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110308124-B | Application of fluorescence probe containing benzothiazole compound in detecting bacterial messenger molecule c-di-GMP | 暨南大学 | 2022-06-03 | — | — | CN | disclosed |