Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 2/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL547979 | 1.00 | ALDH1A1 (0.74) | ALDH1A1TSHRLMNATDP1TP53 | |
| Styrene SCHEMBL28085068 | 1.00 | ALDH1A1 (0.74) | ALDH1A1TSHRLMNATDP1TP53 | |
| Styrene SCHEMBL11586814 | 0.97 | ALDH1A1 (0.70) | ALDH1A1TSHRLMNATDP1TP53 | |
| Styrene SCHEMBL27490580 | 0.97 | ALDH1A1 (0.70) | ALDH1A1TSHRLMNATDP1TP53 | |
| Styrene SCHEMBL7528295 | 0.95 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNATDP1TP53 | |
| Styrene SCHEMBL11673319 | 0.92 | ALDH1A1 (0.70) | ALDH1A1TSHRLMNATDP1TP53 | |
| Styrene SCHEMBL27801477 | 0.89 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNATDP1MAOB | |
| Styrene SCHEMBL18343102 | 0.89 | ALDH1A1 (0.93) | ALDH1A1TSHRLMNATDP1TP53 | |
| Styrene SCHEMBL4282088 | 0.89 | ALDH1A1 (0.93) | ALDH1A1TSHRLMNATDP1TP53 | |
| Styrene SCHEMBL1944454 | 0.89 | ALDH1A1 (0.93) | ALDH1A1TSHRLMNATDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100172861-A1 | Anionic Polymers as Toxin Binders and Antibacterial Agents | GENZYME CORPORATION (US) | 2010-07-08 | — | — | US | disclosed |
| US-7723412-B2 | Stabilization of thermoplastic nanocomposites | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7678369-B2 | Anionic polymers as toxin binders and antibacterial agents | GENZYME CORPORATION (US) | 2010-03-16 | — | — | US | disclosed |
| EP-1824919-B1 | STABILIZED ORGANIC MATERIALS CONTAINING FILLERS | BASF SE (DE) | 2009-12-09 | — | — | EP | disclosed |
| US-20090298978-A1 | Stabilized organic materials containing fillers | CIBA SPECIALTY CHEMICALS CORP. | 2009-12-03 | — | — | US | disclosed |
| EP-1592741-B1 | STABILIZATION OF THERMOPLASTIC NANOCOMPOSITES | CIBA HOLDING INC (CH) | 2009-01-14 | — | — | EP | disclosed |
| US-20080194743-A1 | processing stabilizer selected from the group consisting of hydroxylamine stabilizers, and an antistatic agent selected from an ethoxylated amine and/or an ethoxylated amide, as stabilizers for protecting organic materials | ROTZINGER BRUNO | 2008-08-14 | — | — | US | disclosed |
| US-7375149-B2 | Stabilization of organic materials | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-05-20 | — | — | US | disclosed |
| EP-1824919-A1 | STABILIZED ORGANIC MATERIALS CONTAINING FILLERS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-08-29 | — | — | EP | disclosed |
| EP-1189622-B1 | ANIONIC POLYMERS AS TOXIN BINDERS AND ANTIBACTERIAL AGENTS | GENZYME CORP (US) | 2007-07-25 | — | — | EP | disclosed |
| EP-1149133-B1 | SYNTHETIC POLYMERS COMPRISING ADDITIVE BLENDS WITH ENHANCED EFFECT | CIBA SC HOLDING AG (CH) | 2004-03-17 | — | — | EP | disclosed |
| US-20030138397-A1 | Anionic polymers as toxin binders and antibacterial agents | GELTEX PHARMACEUTICALS, INC. | 2003-07-24 | — | — | US | disclosed |
| US-6517827-B1 | Polystyrene sulfonate polymer; Clostridium difficile | GELTEX PHARMACEUTICALS, INC. | 2003-02-11 | — | — | US | disclosed |
| US-6517826-B1 | Polystyrene sulfonate polymer; Clostridium difficile | GELTEX PHARMACEUTICALS, INC. | 2003-02-11 | — | — | US | disclosed |
| EP-1189622-A2 | ANIONIC POLYMERS AS TOXIN BINDERS AND ANTIBACTERIAL AGENTS | Geltex Pharmaceuticals, Inc. (US) | 2002-03-27 | — | — | EP | disclosed |
| US-6290946-B1 | ADMINISTERING TO THE ANIMAL A THERAPEUTICALLY EFFECTIVE AMOUNT OF A POLYMER HAVING A PLURALITY OF PENDANT ACID FUNCTIONAL GROUPS WHICH ARE DIRECTLY ATTACHED TO THE POLYMER BACKBONE OR ATTACHED TO THE POLYMER BACKBONE BY A SPACER GROUP. | GELTEX PHARMACEUTICALS, INC. | 2001-09-18 | — | — | US | disclosed |
| WO-2000069428-A2 | ANIONIC POLYMERS AS TOXIN BINDERS AND ANTIBACTERIAL AGENTS | GELTEX PHARMACEUTICALS, INC. (US) | 2000-11-23 | — | — | WO | disclosed |
| EP-0463400-B1 | Transparencies | XEROX CORP (US) | 1997-04-02 | — | — | EP | disclosed |
| US-5202205-A | TRANSPARENCIES COMPRISING METAL HALIDE OR UREA ANTISTATIC LAYER | XEROX CORPORATION (US) | 1993-04-13 | — | — | US | disclosed |
| EP-0463400-A1 | Transparencies | XEROX CORPORATION (US) | 1992-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100172861-A1 | Anionic Polymers as Toxin Binders and Antibacterial Agents | MSN, ANTXR2, PNKP | ALDH1A1 4470/4885TSHR 1345/4885LMNA 2848/4885 |
| US-20030138397-A1 | Anionic polymers as toxin binders and antibacterial agents | MSN, ANTXR2, PNKP | ALDH1A1 4470/4885TSHR 1345/4885LMNA 2848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.